Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir Extended-Release Tablets

• It is used to treat hepatitis C infection.

• If you have an allergy to this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets) or any part of this medicine.
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you have liver problems other than hepatitis C.
• If you have had a severe skin reaction after taking ritonavir.
• If you are taking a drug that contains ethinyl estradiol, like certain birth control pills. Do not take a drug that contains ethinyl estradiol while taking this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets) and for some time after stopping this medicine. Your doctor will tell you when you can start taking a drug that contains ethinyl estradiol again after stopping this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets).
• If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this medicine, like certain drugs that are used for high cholesterol, HIV, or seizures. There are many drugs that must not be taken with this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets).

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Use this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with a meal.
• Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well.
• It is important that you do not miss or skip a dose of this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets) during treatment.
• Swallow whole. Do not chew, break, or crush.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.
• If you are not sure what to do if you miss a dose, call your doctor.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Any skin reaction.
• Feeling very tired or weak.
• Very bad and sometimes deadly liver problems have happened with this medicine. Some people have needed a liver transplant. These problems most often happened within 1 to 4 weeks of starting treatment. Most people who have had them already had liver problems before starting this medicine (ombitasvir, paritaprevir, ritonavir, and dasabuvir extended-release tablets). Tell your doctor right away if you have signs of liver problems like dark urine, feeling tired or weak, change in thinking clearly and with logic, not hungry, upset stomach or stomach pain, stomach swelling, light-colored stools, throwing up, or yellow skin or eyes.
• A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.