Telavancin Injection

Telavancin injection comes as a powder to be mixed with liquid and injected intravenously (into a vein). It is usually infused (injected slowly) over a period of 60 minutes once every 24 hours for 7 to 21 days. The length of your treatment depends on the type of infection you have and how your body responds to the medication.

You may experience a reaction while you receive a dose of telavancin injection, usually during your infusion or soon after your infusion has completed. Tell your doctor immediately if you experience any of these symptoms while you receive telavancin injection: difficulty swallowing or breathing, swelling of your tongue, lips, throat or face, hoarseness, itching, hives, rash, flushing of the upper body, fast heartbeat, or feeling faint or dizzy.

You may receive telavancin injection in a hospital or you may administer the medication at home. If you will be using telavancin injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing telavancin injection.

You should begin to feel better during the first few days of treatment with telavancin injection. If your symptoms do not improve or get worse, tell your doctor.

Use telavancin injection until you finish the prescription, even if you feel better. If you stop using telavancin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Before using telavancin injection,

• tell your doctor and pharmacist if you are allergic to telavancin , vancomycin, any other medications, or any of the ingredients in telavancin injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
• tell your doctor if you are receiving heparin. Your doctor will probably tell you not to use heparin if you are receiving telavancin injection.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anagrelide (Agrylin); anticoagulants (''blood thinners'') such as warfarin (Coumadin); azithromycin (Zithromax); chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram; donepezil (Aricept); dronedarone (Multaq); escitalopram (Lexapro); haloperidol (Haldol); medications that control the heart rhythm or rate such as amiodarone (Cordarone, Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), procainamide, quinidine, and sotalol (Betapace, Sorine, Sotylize); levofloxacin (Levaquin); methadone (Dolophine, Methadose); ondansetron (Zofran, Zyplenz); pimozide (Orap); vandetanib (Caprelsa); and thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with telavancin injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
• tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (rare heart problem that may cause irregular heartbeat, fainting, or sudden death) and if you have or have ever had heart disease.
• tell your doctor if you are breastfeeding.

Unless your doctor tells you otherwise, continue your normal diet.

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