Tritec

Serious side effects have been reported with ranitidine including:

• Ranitidine is cleared from the body by the kidneys and liver. Talk to your doctor if you have kidney or liver disease.
• This medication can cause porphyria attacks in people with acute porphyria, a rare, inherited condition usually affecting the skin or nervous system. Do not take ranitidine if you have a history of acute porphyria (a disease affecting heme in red blood cells). 
• Hypersensitivity reaction:  An allergic reaction to ranitidine is possible.  Call your doctor if you experience one or more of the following symptoms of a hypersensitivity reaction:
  • difficulty swallowing or breathing
  • hoarseness
  • fever
  • rash
  • swelling

Ranitidine can cause dizziness and drowsiness.  Do not drive or operate machinery until you know how ranitidine affects you.

Do not take ranitidine if you:

• are allergic to ranitidine (Zantac)

Before taking ranitidine, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

• have a history of kidney or liver disease
• have a history of acute porphyria (a disease affecting heme in red blood cells)
• are allergic to ranitidine (Zantac)
• are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are breastfeeding or plan to breastfeed. The active ingredient in ranitidine is excreted in human breast milk. The effect of ranitidine on the nursing infant is not known.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your weight
• your height
• your age
• your gender

Injectable:

• Into the muscle (IM) Injection: 50 mg every 6 to 8 hours
• Into the vein (IV) Itravenous Injection:
  • ​Intermittent Bolus: 50 mg (2 mL) every 6 to 8 hours
  • Intermittent Infusion: 50 mg (2 mL) every 6 to 8 hours
  • Continuous Infusion: Deliver at a rate of 6.25 mg/hour
  • For treatment of Zollinger-Ellison: Start the infusion at a rate of 1 mg/kg per hour. 

​Oral 

• Adult Use
  •  Active Duodenal Ulcer - The current recommended adult oral dosage of ranitidine for duodenal ulcer is 150 mg of ranitidine twice daily. An alternative dosage of 300 mg of syrup once daily after the evening meal or at bedtime.
  • Maintenance of Healing of Duodenal Ulcers - The current recommended adult oral dosage is 150 mg at bedtime.
  • Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome) - The current recommended adult oral dosage is 150 mg twice daily. In some patients it may be necessary to administer ranitidine 150-mg doses more frequently. Dosages up to 6 grams/day have been employed in patients with severe disease.
  • Benign Gastric Ulcer - The current recommended adult oral dosage is 150 mg twice daily.
  • Maintenance of Healing of Gastric Ulcers - The current recommended adult oral dosage is 150 mg at bedtime.
  • GERD - The current recommended adult oral dosage is 150 mg twice daily.
  • Erosive Esophagitis - ​​The current recommended adult oral dosage is 150 mg 4 times daily.
  • Maintenance of Healing of Erosive Esophagitis - The current recommended adult oral dosage is 150 mg twice daily.
• Pediatric Use
  • Treatment of Duodenal and Gastric Ulcers - The recommended oral dose for the treatment of active duodenal and gastric ulcers is 2 to 4 mg/kg twice daily to a maximum of 300 mg/day.
  • Maintenance of Healing of Duodenal and Gastric Ulcers - The recommended oral dose for the maintenance of healing of duodenal and gastric ulcers is 2 to 4 mg/kg once daily to a maximum of 150 mg/day.
  • Treatment of GERD and Erosive Esophagitis - Published literature supports a dosage of 5 to 10 mg/kg/day, usually given as 2 divided doses. 

If you take too much this medication, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.