Thiamine

Before taking thiamine,

• tell your doctor and pharmacist if you are allergic to thiamine or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including other vitamins.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking thiamine, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking thiamine.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Thiamine is a prescription medication used to treat thiamine deficiency or beri beri. Thiamine belongs to a group of drugs called vitamins, which help to restore levels of this vitamin in the body.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with thiamine. See the “Drug Precautions” section.

Common side effects of thiamine include the following:

• sensitivity, redness, warmth, and itching at site of injection
• nausea
• restlessness

This is not a complete list of thiamine side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Treatment of thiamine deficiency, beriberi (dry or wet variety), Wernicke encephalopathy, infantile beriberi with acute collapse, cardiovascular disease due to thiamine deficiency, neuritis associated with pregnancy, or when giving IV dextrose to individuals with marginal thiamine status to avoid precipitation of heart failure; dietary supplement.

A 100 mg/mL oral suspension may be made with commercially available thiamine powder. Add 10 g of powder to a mortar. Add small portions of a 1:1 mixture of Ora-Sweet® and Ora-Plus® and mix to a uniform paste; mix while adding the vehicle in equal proportions to almost 100 mL; transfer to a calibrated bottle, rinse mortar with vehicle, and add sufficient quantity of vehicle to make 100 mL. Label "shake well". Stable 91 days under refrigeration or at room temperature.

Injection: Store at 15°C to 30°C (59°F to 86°F). Protect from light.

Adverse reactions reported with injection. Frequency not defined.

Central nervous system: Flushing sensation, restlessness

Dermatologic: Diaphoresis, pruritus, skin sclerosis (at the injection site following IM administration), urticaria

Gastrointestinal: Nausea

Hematologic & oncologic: Hemorrhage (into the gastrointestinal tract)

Hypersensitivity: Anaphylaxis (following IV administration), angioedema, hypersensitivity reaction (following IV administration)

Local: Tenderness at injection site (following IM administration)

Neuromuscular & skeletal: Weakness

Respiratory: Cyanosis, pharyngeal edema, pulmonary edema