Chloroptic

Chioramphenicol should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. (See Boxed Warning)

Chloroptic (chloramphenicol) is indicated for the treatment of surface ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. Chloramphenicol is active against the following common bacterial eye pathogens: Staphylococcus aureus; streptococci, including Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzea, Klebsiella/Enterobacter species; Moraxella lacunata (Morax-Axenfeld bacillus); and Neisseria species. Chloramphenicol does not provide adequate coverage against: Pseudomonas aeruginosa or Serratia marcescens.

Exact incidence figures are not available since no denominator of treated patients is available.

The most serious reaction following prolonged or frequent intermittent use of topical chloramphenicol is bone marrow aplasia.

The most frequently reported adverse reactions have been burning, stinging, ocular irritation, and conjunctival hyperemia. Blood dyscrasias, allergic or inflammatory reactions due to individual hypersensitivity, angioneurotic edema, urticaria, vesicular and maculopapular dermatitis have also been reported (See Warnings and Box Warning).

Chloroptic is part of the drug classes:

• AMPHENICOLS

• Antiinfectives for treatment of acne

• Other antibiotics for topical use