Thrombin-JMI

Name: Thrombin-JMI

Manufacturer

  • Jones Pharma Incorporated

  • King Pharmaceuticals, Inc.

  • Monarch Pharmaceuticals, Inc.

Actions

  • Causes clotting of whole blood or plasma without the addition of other substances.100 b Affects hemostasis principally by converting fibrinogen to fibrin; several other mechanisms (e.g., stimulation of platelet release reaction, aggregation of platelets) may be involved.100 109 b

  • Rate of blood clotting depends on concentration of thrombin and fibrinogen.100 b

  • Does not clot blood when clotting defect is the rare absence of fibrinogen.100

Adverse Reactions

Allergic reactions may be encountered in persons known to be sensitive to bovine materials. Inhibitory antibodies which interfere with hemostasis may develop in a small percentage of patients. See WARNING .

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