Tiotropium and olodaterol Inhalation
Name: Tiotropium and olodaterol Inhalation
Before Using tiotropium and olodaterol
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tiotropium and olodaterol, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to tiotropium and olodaterol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of inhaled tiotropium and olodaterol combination in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of inhaled tiotropium and olodaterol combination in the elderly.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking tiotropium and olodaterol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using tiotropium and olodaterol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Amitriptyline
- Amoxapine
- Atropine
- Belladonna
- Benztropine
- Biperiden
- Brompheniramine
- Bupropion
- Carbinoxamine
- Carisoprodol
- Chlorpheniramine
- Chlorpromazine
- Clemastine
- Clidinium
- Clomipramine
- Clozapine
- Cyclobenzaprine
- Cyclopentolate
- Cyproheptadine
- Darifenacin
- Desipramine
- Dicyclomine
- Dimenhydrinate
- Diphenhydramine
- Donepezil
- Doxepin
- Flavoxate
- Fluphenazine
- Glycopyrrolate
- Homatropine
- Hydroxyzine
- Hyoscyamine
- Imipramine
- Ipratropium
- Loxapine
- Meclizine
- Mepenzolate
- Nortriptyline
- Olanzapine
- Orphenadrine
- Oxitropium Bromide
- Oxybutynin
- Paroxetine
- Perphenazine
- Pimozide
- Pipenzolate Bromide
- Pirenzepine
- Prochlorperazine
- Procyclidine
- Promethazine
- Propantheline
- Propiverine
- Protriptyline
- Scopolamine
- Solifenacin
- Stramonium
- Terodiline
- Thioridazine
- Thiothixene
- Tizanidine
- Tolterodine
- Trifluoperazine
- Trihexyphenidyl
- Trimipramine
- Tropicamide
- Trospium
- Umeclidinium
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of tiotropium and olodaterol. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma—Use is not recommended in patients with this condition.
- Diabetes or
- Difficult urination or
- Enlarged prostate or
- Glaucoma, narrow angle or
- Heart or blood vessel disease (eg, coronary insufficiency, obstructive cardiomyopathy) or
- Heart rhythm problems (eg, arrhythmia, QT prolongation) or
- Hyperglycemia (high blood sugar) or
- Hypertension (high blood pressure) or
- Hyperthyroidism (overactive thyroid) or
- Hypokalemia (low potassium levels in the blood) or
- Seizures or
- Urinary bladder blockage—Use with caution. May make these conditions worse.
- Kidney disease, moderate to severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.