Tobramycin Sulfate ADD-Vantage injection

Name: Tobramycin Sulfate ADD-Vantage injection

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Tobramycin Sulfate ADD-Vantage (tobramycin injection) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tobramycin can damage nerves and may cause hearing loss that may be permanent. Tell your doctor right away if you have:

  • numbness, tingling, muscle stiffness or uncontrolled twitching;

  • dizziness, spinning sensation, seizure (convulsions); or

  • hearing loss, or a ringing or roaring sound in your ears (even after you have stopped using tobramycin injection).

Call your doctor at once if you have:

  • swelling, rapid weight gain, little or no urinating;

  • confusion, loss of appetite, vomiting, pain in your side or lower back;

  • fever; or

  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • headache;

  • lack of energy;

  • mild rash or itching;

  • nausea, vomiting, diarrhea; or

  • pain where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tobramycin Sulfate ADD-Vantage (tobramycin injection)?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with tobramycin, especially:

  • diuretics--ethacrynic acid, furosemide.

Tobramycin can harm your kidneys. This effect is increased when you also use certain other medicines, especially:

  • cisplatin;

  • injected antibiotics--amikacin, colistimethate, kanamycin, gentamicin, polymyxin B, streptomycin, vancomycin; or

  • certain antibiotics taken by mouth--neomycin, paromomycin.

This list is not complete. Other drugs may interact with tobramycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

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