Timentin Add-Vantage

Timentin is a prescription medication used to treat bacterial infections of the stomach, skin, lungs, bone, joint, and urinary tract. It is also used to treat gynecological infections. It contains 2 medications, ticarcillin and clavulanic acid.

Ticarcillin belongs to a group of drugs called penicillin antibiotics, which help stop the growth of bacteria. Clavulanic acid belongs to a group of drugs called beta lactamase inhibitors, which work by preventing bacteria from destroying ticarcillin.

This medication is available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

Common side effects of Timentin include rash, nausea, diarrhea, and irritation at the site of injection.

Timentin is a prescription medication used to treat bacterial infections of the stomach, skin, lungs, bone, joint, and urinary tract. It is also used to treat gynecological infections.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Timentin ADD-Vantage is part of the drug class:

• Penicillins with extended spectrum

This medication is available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

TIMENTIN is a sterile injectable antibacterial combination consisting of the semisynthetic antibiotic ticarcillin disodium, and the β-lactamase inhibitor clavulanate potassium (the potassium salt of clavulanic acid) for intravenous administration. Ticarcillin is derived from the basic penicillin nucleus, 6-amino-penicillanic acid.

Chemically, ticarcillin disodium is N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-3-thiophenemalonamic acid disodium salt and may be represented as:

Clavulanic acid is produced by the fermentation of Streptomycesclavuligerus. It is a β-lactam structurally related to the penicillins and possesses the ability to inactivate a wide variety of β-lactamases by blocking the active sites of these enzymes. Clavulanic acid is particularly active against the clinically important plasmid-mediated β-lactamases frequently responsible for transferred drug resistance to penicillins and cephalosporins.

Chemically, clavulanate potassium is potassium (Z)-(2R ,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate and may be represented structurally as:

TIMENTIN is supplied as a white to pale yellow powder for reconstitution. TIMENTIN is very soluble in water, its solubility being greater than 600 mg/mL. The reconstituted solution is clear, colorless or pale yellow, having a pH of 5.5 to 7.5.

For the 3.1-gram dosage of TIMENTIN, the theoretical sodium content is 4.51 mEq (103.6 mg) per gram of TIMENTIN. The theoretical potassium content is 0.15 mEq (6 mg) per gram of TIMENTIN.