Pamine Forte

Contraindications

Hypersensitivity to methscopolamine or related compounds

Closed-angle glaucoma, myasthenia gravis, hemorrhage with cardiovascular instability, paralytic ileus, intestinal atony of elderly/debilitated patient, obstructive uropathy, toxic megacolon, GI obstruction, tachycardia secondary to cardiac insufficiency or thyrotoxicosis

Cautions

Renal/hepatic impairment, BPH, CHF, CAD, HTN, COPD, hiatal hernia, reflux esophagitis, mitral stenosis, brain damage or spastic paralysis in children, salivary secretion disorder, Down synd, autonomic neuropathy, hyperthyroidism, tachyarrythmia, toxin-mediated diarrhea

Elderly (see Beers Criteria)

Risk of heat prostration in high environmental temperature

May produce drowsiness or blurred vision, caution if performing hazardous tasks

Use low dosage for patient with increased susceptibility to adverse antimuscarinic effects

Methscopolamine reduces the secretions of certain organs in the body, such as the stomach.

Methscopolamine is used to reduce stomach acid secretion to help control peptic ulcers.

This medication does not help heal a stomach ulcer.

Methscopolamine may also be used for other purposes not listed in this medication guide.

Many drugs can interact with methscopolamine. Below is just a partial list. Tell your doctor if you are using:

• digoxin (digitalis, Lanoxin);

• an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), doxepin (Sinequan), imipramine (Janimine, Tofranil), and others;

• medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine);

• atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

• bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

• glycopyrrolate (Robinul);

• mepenzolate (Cantil);

• bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or

• irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

This list is not complete and there may be other drugs that can interact with methscopolamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

• It is used to treat GI (gastrointestinal) ulcers.

Use Pamine Forte as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take 30 minutes before meals and at bedtime.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Feeling sleepy.
• Blurred eyesight.
• Dizziness.
• Headache.
• Hard stools (constipation).
• Dry mouth.
• Change in taste.
• Upset stomach or throwing up.
• Less sweating.
• Feeling tired or weak.
• Not able to sleep.
• Feeling nervous and excitable.
• Bloating.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Pamine Forte or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Pamine Forte. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Applies to methscopolamine: oral tablet

Cardiovascular

Cardiovascular side effects have included tachycardia and palpitations.[Ref]

Hypersensitivity

Hypersensitivity side effects have included drug idiosyncrasies and anaphylaxis.[Ref]

Nervous system

Nervous system side effects have included headache, nervousness, mental confusion, drowsiness, and dizziness.[Ref]

Ocular

Ocular side effects have included blurred vision, dilation of pupil, cycloplegia, and increased ocular tension.[Ref]

Renal

Renal side effects have included urinary hesitancy and urinary retention.[Ref]

Gastrointestinal

Gastrointestinal side effects have included xerostomia, nausea, vomiting, constipation, and bloating.[Ref]

Dermatologic

Dermatologic side effects have included decreased sweating, urticaria, and other dermal manifestations.[Ref]

Endocrine

Endocrine side effects have included suppression of lactation.[Ref]

Genitourinary

Genitourinary side effects have included impotence.[Ref]

Other

Other side effects have included weakness, insomnia, and loss of taste.[Ref]

Some side effects of Pamine Forte may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.