P-V-Tussin Syrup

Name: P-V-Tussin Syrup

P-V-Tussin Syrup Overview

P-V-Tussin Syrup is a brand name medication included in the following groups of medications: Substituted alkylamines, Opium alkaloids and derivatives, Sympathomimetics. For more information about P-V-Tussin Syrup see its generics Chlorphenamine, Hydrocodone, Pseudoephedrine

What should I discuss with my healthcare provider before taking P-V-Tussin Syrup (chlorpheniramine, hydrocodone, and pseudoephedrine)?

You should not use this medicine if you are allergic to chlorpheniramine or hydrocodone; or if you have:

  • severe coronary artery disease;

  • severe or uncontrolled high blood pressure; or

  • narrow-angle glaucoma.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure chlorpheniramine, hydrocodone, and pseudoephedrine is safe for you, tell your doctor if you have ever had:

  • asthma or other breathing problems;

  • a head injury or brain tumor;

  • a stomach or intestinal disorder;

  • enlarged prostate, urination problems;

  • diabetes;

  • liver or kidney disease;

  • Addison's disease (an adrenal gland disorder);

  • a thyroid disorder; or

  • alcoholism or drug addiction.

If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether chlorpheniramine, hydrocodone, and pseudoephedrine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

This medicine should not be given to a anyone younger than 18 years old.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What should I avoid while taking P-V-Tussin Syrup (chlorpheniramine, hydrocodone, and pseudoephedrine)?

Do not drink alcohol. Dangerous side effects or death could occur.

This medicine may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.

Ask a doctor or pharmacist before using any other cold, allergy, cough, or sleep medicine. Many combination medicines contain antihistamines, decongestants, or cough suppressants. Taking certain products together can cause you to get too much of a certain drug.

What other drugs will affect P-V-Tussin Syrup (chlorpheniramine, hydrocodone, and pseudoephedrine)?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • medicine for a stomach or intestinal disorder;

  • an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others; or

  • a sedative--Valium, diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others.

This list is not complete. Other drugs may interact with chlorpheniramine, hydrocodone, and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

For the Consumer

Applies to chlorpheniramine / hydrocodone / pseudoephedrine: oral capsule, oral liquid, oral solution, oral suspension, oral syrup, oral tablet

Along with its needed effects, chlorpheniramine / hydrocodone / pseudoephedrine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking chlorpheniramine / hydrocodone / pseudoephedrine:

More common
  • Fainting
  • lightheadedness
  • shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet
Incidence not known
  • Abdominal or stomach cramps or pain
  • bloating
  • blurred vision
  • bulging soft spot on the head of an infant
  • change in the ability to see colors, especially blue or yellow
  • confusion
  • constipation
  • convulsions
  • decrease in the frequency of urination
  • decrease in the urine volume
  • diarrhea
  • difficult or troubled breathing
  • difficulty in passing urine (dribbling)
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • drowsiness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • irregular, fast or slow, or shallow breathing
  • loss of appetite
  • nervousness
  • painful urination
  • pale or blue lips, fingernails, or skin
  • pounding in the ears
  • shortness of breath
  • sore throat
  • spasm of the throat
  • sweating
  • tightness of the chest
  • unusual tiredness or weakness
  • vomiting

Some side effects of chlorpheniramine / hydrocodone / pseudoephedrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Disturbed color perception
  • double vision
  • dry mouth
  • false or unusual sense of well-being
  • fear or nervousness
  • halos around lights
  • hyperventilation
  • nausea
  • night blindness
  • overbright appearance of lights
  • relaxed and calm
  • restlessness
  • sleepiness or unusual drowsiness
  • sleeplessness
  • trouble sleeping
  • tunnel vision
  • unable to sleep
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Incidence not known
  • Acid or sour stomach
  • belching
  • bigger, dilated, or enlarged pupils (black part of the eye)
  • bloating
  • change in color vision
  • chills
  • cold sweats
  • coma
  • continuing ringing or buzzing or other unexplained noise in the ears
  • cool, pale skin
  • darkened urine
  • depression
  • difficulty seeing at night
  • feeling of constant movement of self or surroundings
  • fever
  • flushing or redness of the skin
  • full feeling
  • hearing loss
  • heartburn
  • hives or welts
  • increased appetite
  • increased hunger
  • increased in sexual ability, desire, drive, or performance
  • increased interest in sexual intercourse
  • increased sensitivity of the eyes to sunlight
  • increased sweating
  • indigestion
  • itching skin
  • loss of appetite
  • nightmares
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pressure in the stomach
  • seizures
  • sensation of spinning
  • skin rash
  • slurred speech
  • stomach discomfort or upset
  • sugar in the urine
  • swelling of the abdominal or stomach area
  • swelling of the breasts or breast soreness in both females and males
  • unusually warm skin
  • watering of the eyes
  • yellow eyes or skin

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