Moclobemide (Oral Route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Older adults are especially sensitive to the effects of moclobemide. This may increase the chance of side effects during treatment. Dizziness or lightheadedness may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to these effects.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Amitriptyline
• Amoxapine
• Amphetamine
• Apraclonidine
• Atomoxetine
• Benzphetamine
• Brimonidine
• Bupropion
• Carbamazepine
• Carbidopa
• Carbinoxamine
• Citalopram
• Clomipramine
• Cyclobenzaprine
• Cyproheptadine
• Desipramine
• Desvenlafaxine
• Dexfenfluramine
• Dexmethylphenidate
• Dextroamphetamine
• Dextromethorphan
• Diethylpropion
• Dothiepin
• Doxepin
• Doxylamine
• Escitalopram
• Fenfluramine
• Fluoxetine
• Fluvoxamine
• Guanadrel
• Guanethidine
• Hydroxytryptophan
• Imipramine
• Isometheptene
• Levodopa
• Levomethadyl
• Levomilnacipran
• Lisdexamfetamine
• Lofepramine
• Maprotiline
• Mazindol
• Meperidine
• Methadone
• Methamphetamine
• Methotrimeprazine
• Methyldopa
• Methylphenidate
• Milnacipran
• Mirtazapine
• Nefopam
• Nortriptyline
• Opicapone
• Opipramol
• Paroxetine
• Phendimetrazine
• Phenmetrazine
• Phentermine
• Phenylalanine
• Protriptyline
• Pseudoephedrine
• Reserpine
• Safinamide
• Selegiline
• Sertraline
• Sibutramine
• Sumatriptan
• Tapentadol
• Tetrabenazine
• Trazodone
• Trimipramine
• Tryptophan
• Venlafaxine
• Vilazodone
• Vortioxetine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Altretamine
• Atropine
• Buprenorphine
• Buspirone
• Cilostazol
• Clovoxamine
• Difenoxin
• Diphenoxylate
• Dolasetron
• Droperidol
• Ethchlorvynol
• Femoxetine
• Fentanyl
• Frovatriptan
• Granisetron
• Guarana
• Hydrocodone
• Hydromorphone
• Iobenguane I 123
• Kava
• Licorice
• Ma Huang
• Mate
• Methylene Blue
• Morphine
• Morphine Sulfate Liposome
• Naratriptan
• Nebivolol
• Nefazodone
• Oxycodone
• Oxymetazoline
• Palonosetron
• Reboxetine
• St John's Wort
• Tramadol
• Tyrosine
• Ziprasidone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acarbose
• Chlorpropamide
• Ginseng
• Glimepiride
• Glipizide
• Glyburide
• Insulin
• Insulin Aspart, Recombinant
• Insulin Bovine
• Insulin Degludec
• Insulin Detemir
• Insulin Glargine, Recombinant
• Insulin Glulisine
• Insulin Lispro, Recombinant
• Metformin
• Nateglinide
• Repaglinide
• Tolazamide
• Tolbutamide

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Avocado
• Bitter Orange

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Hypertension—May make this condition worse.
• Liver disease—Effects may be increased because of slower removal of the medicine from the body.