Moduretic 5-50

Name: Moduretic 5-50

Moduretic 5-50 brand name
Moduretic 5-50 side effects
Moduretic 5-50 drug
Moduretic 5-50 effects of
Moduretic 5-50 dosage
Moduretic 5-50 dosage forms
Moduretic 5-50 the effects of

US Brand Name

Moduretic 5-50

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Potassium Containing Food

What should I discuss with my healthcare provider before taking Moduretic 5-50 (hydrochlorothiazide and amiloride)?

You should not use this medication if you are allergic to hydrochlorothiazide or amiloride, or if you have:

kidney disease or are unable to urinate;
high potassium levels (hyperkalemia); or
if you are taking potassium supplements.

Some medicines can cause unwanted or dangerous effects when used with hydrochlorothiazide and amiloride. Your doctor may need to change your treatment plan if you use potassium supplements or certain diuretics (spironolactone, triamterene).

If you have diabetes, do not use hydrochlorothiazide and amiloride together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

To make sure hydrochlorothiazide and amiloride is safe for you, tell your doctor if you have:

high cholesterol, heart disease, coronary artery disease;
cirrhosis or other liver disease;
glaucoma;
a breathing disorder;
gout; or
an allergy to sulfa drugs or penicillin.

This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using hydrochlorothiazide and amiloride.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Moduretic 5-50 (hydrochlorothiazide and amiloride)?

Drinking alcohol can increase certain side effects of hydrochlorothiazide and amiloride.

Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking hydrochlorothiazide and amiloride.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Commonly used brand name(s)

In the U.S.

Moduretic 5-50

Available Dosage Forms:

Tablet

Therapeutic Class: Diuretic, Potassium Sparing/Thiazide Combination

Pharmacologic Class: Amiloride

Chemical Class: Thiazide

Before Using Moduretic 5-50

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of amiloride and hydrochlorothiazide combination in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of amiloride and hydrochlorothiazide combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney or heart problems, which may require an adjustment in the dose for patients receiving amiloride and hydrochlorothiazide combination .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Dofetilide
Eplerenone
Triamterene

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aceclofenac
Acemetacin
Acetyldigoxin
Alacepril
Amphetamine
Amtolmetin Guacil
Arginine
Arsenic Trioxide
Aspirin
Benazepril
Benzphetamine
Bromfenac
Bufexamac
Bupropion
Captopril
Celecoxib
Choline Salicylate
Cilazapril
Clonixin
Cyclophosphamide
Delapril
Deslanoside
Dexibuprofen
Dexketoprofen
Dextroamphetamine
Diclofenac
Diflunisal
Digitalis
Digitoxin
Digoxin
Dipyrone
Dofetilide
Droperidol
Droxicam
Enalaprilat
Enalapril Maleate
Etodolac
Etofenamate
Etoricoxib
Felbinac
Fenoprofen
Fepradinol
Feprazone
Flecainide
Floctafenine
Flufenamic Acid
Flurbiprofen
Fosinopril
Ibuprofen
Imidapril
Indomethacin
Ketanserin
Ketoprofen
Ketorolac
Levomethadyl
Lisdexamfetamine
Lisinopril
Lithium
Lornoxicam
Loxoprofen
Lumiracoxib
Meclofenamate
Mefenamic Acid
Meloxicam
Methamphetamine
Methotrexate
Metildigoxin
Moexipril
Morniflumate
Nabumetone
Naproxen
Nepafenac
Niflumic Acid
Nimesulide
Nimesulide Beta Cyclodextrin
Ouabain
Oxaprozin
Oxyphenbutazone
Parecoxib
Pentopril
Perindopril
Phenylbutazone
Piketoprofen
Piroxicam
Potassium
Pranoprofen
Proglumetacin
Propyphenazone
Proquazone
Proscillaridin
Quinapril
Ramipril
Rofecoxib
Salicylic Acid
Salsalate
Sodium Salicylate
Sotalol
Spirapril
Sulindac
Temocapril
Tenoxicam
Tiaprofenic Acid
Tolfenamic Acid
Tolmetin
Trandolapril
Trimethoprim
Valdecoxib
Zofenopril

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aminolevulinic Acid
Bepridil
Carbamazepine
Carbenoxolone
Cholestyramine
Ginkgo
Gossypol
Licorice
Quinidine
Topiramate

Interactions with Food/Tobacco/Alcohol

Potassium Containing Food