Meclizine Hydrochloride

Antiemetic; piperazine-derivative antihistamine.a b c

Storage

Oral

Tight, light-resistant container at 15–30°C.a c d

• Exhibits CNS depressant, anticholinergic, antiemetic, antispasmodic, and local anesthetic effects in addition to antihistaminic activity.a

• Depresses labyrinth excitability and conduction in vestibular-cerebellar pathways.a

• Antiemetic and antimotion-sickness actions result, at least in part, from central anticholinergic and CNS depressant properties.a

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name