Ixabepilone (Intravenous Route)

1. Ixempra

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ixabepilone injection in the elderly.

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to a medicine (e.g., Taxol®) that contains Cremophor® EL or polyoxyethylated castor oil or
• Liver disease, severe or
• Neutropenia (low white blood cell count) or
• Thrombocytopenia (low platelet count)—Should not be used in patients with these conditions.

• Diabetes—Use with caution. This medicine may increase your chance of having nerve problems.

• Heart disease, or history of or
• Nerve problems (e.g., peripheral neuropathy)—Use with caution. May make these conditions worse.

• Liver disease, mild—Use with caution. This medicine should not be given with capecitabine to patients with this condition.