Methoxsalen (Systemic)
Name: Methoxsalen (Systemic)
Pronunciation
(meth OKS a len)
Index Terms
- 8-Methoxypsoralen
- 8-MOP
- Methoxypsoralen
Brand Names U.S.
- 8-Mop [DSC]
- Oxsoralen Ultra
- Uvadex
Dosing Geriatric
Refer to adult dosing.
Dosing Hepatic Impairment
There are no dosage adjustments provided in manufacturer’s labeling; use with caution.
Reconstitution
Solution should not be diluted. Vial contents should be injected into the photopheresis system immediately after being drawn up into a syringe. For single use only; discard unused portion immediately. Solution exposed to a plastic syringe for >1 hour should be discarded.
Administration
Oral: To reduce nausea, capsules should be administered with food or milk.
Extracorporeal: Do not inject solution directly into patients. Vial contents should be injected into the photoactivation bag of the UVAR XTS or CELLEX Photopheresis System immediately after being drawn up into a syringe. Solution can adsorb onto PVC and plastics; only UVAR XTS or CELLEX photopheresis procedural kits supplied for use with the instrument should be used to administer the product.