Methoxsalen (Systemic)

Name: Methoxsalen (Systemic)

Pronunciation

(meth OKS a len)

Index Terms

  • 8-Methoxypsoralen
  • 8-MOP
  • Methoxypsoralen

Brand Names U.S.

  • 8-Mop [DSC]
  • Oxsoralen Ultra
  • Uvadex

Dosing Geriatric

Refer to adult dosing.

Dosing Hepatic Impairment

There are no dosage adjustments provided in manufacturer’s labeling; use with caution.

Reconstitution

Solution should not be diluted. Vial contents should be injected into the photopheresis system immediately after being drawn up into a syringe. For single use only; discard unused portion immediately. Solution exposed to a plastic syringe for >1 hour should be discarded.

Administration

Oral: To reduce nausea, capsules should be administered with food or milk.

Extracorporeal: Do not inject solution directly into patients. Vial contents should be injected into the photoactivation bag of the UVAR XTS or CELLEX Photopheresis System immediately after being drawn up into a syringe. Solution can adsorb onto PVC and plastics; only UVAR XTS or CELLEX photopheresis procedural kits supplied for use with the instrument should be used to administer the product.

(web3)