Cyproheptadine-oral

Cyproheptadine is used for treating various types of allergic reactions and the skin manifestations of allergic reactions.

It's off-label uses (non-FDA approved) include:

• Spasticity associated with spinal cord injury
• Prevention of migraine headaches

Side effects of include:

• Drowsiness
• Sedation
• Dizziness
• Restlessness
• insomnia
• Tremors
• Euphoria
• Nervousness
• Irritability
• Delirium
• Seizures
• Psychosis
• Paresthesia
• Weakness
• Palpitation
• Fast heart beat
• Palpitation
• High or low blood pressure
• Anorexia
• Nausea
• Vomiting
• Diarrhea
• Constipation
• Cholestasis
• Hepatitis
• Eczema
• Itching
• Blurred vision
• Double Vision
• Ringing in the ears
• Urinary retention
• Wheezing
• Nasal stuffiness

Other side effects that have been reported include:

• Vertigo
• Sweating
• Chills
• Early menses
• Headache
• impotence
• Dryness of mouth, nose, and throat
• Facial dyskinesia
• Tightness of chest

Antihistamines may reduce mental alertness, however, they may occasionally produce excitation in children.

Patients should be warned about driving a car or operating machinery and participating in other activities that require mental alertness and motor coordination.

Antihistamines may add to the sedative effects of alcohol, hypnotics, sedatives, tranquilizers, and anti-anxiety drugs.

Antihistamines are more likely to cause dizziness, sedation, and hypotension (low blood pressure) in elderly patients.

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Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Do not use with any other antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray) because increased side effects may occur.

This medication may interfere with certain laboratory tests (including allergy skin testing, metyrapone test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, seizures, widened pupils. In children, mental/mood changes (such as restlessness, irritability, hallucinations) may occur before drowsiness.

Notes

Do not share this medication with others.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not freeze the liquid form of this medication. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised July 2017. Copyright(c) 2017 First Databank, Inc.