Cemill 1000
Name: Cemill 1000
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Before Using Cemill 1000
If you are taking this dietary supplement without a prescription, carefully read and follow any precautions on the label. For this supplement, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Problems in children have not been reported with intake of normal daily recommended amounts.
Geriatric
Problems in older adults have not been reported with intake of normal daily recommended amounts.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast Feeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this dietary supplement, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this dietary supplement with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Amygdalin
- Deferoxamine
Using this dietary supplement with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Indinavir
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this dietary supplement. Make sure you tell your doctor if you have any other medical problems, especially:
- Blood problems—High doses of vitamin C may cause certain blood problems
- Type 2 diabetes mellitus—Very high doses of vitamin C may interfere with tests for sugar in the urine
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency—High doses of vitamin C may cause hemolytic anemia
- Kidney stones (history of)—High doses of vitamin C may increase risk of kidney stones in the urinary tract
Precautions While Using Cemill 1000
Vitamin C is not stored in the body. If you take more than you need, the extra vitamin C will pass into your urine. Very large doses may also interfere with tests for sugar in diabetics and with tests for blood in the stool.
For Healthcare Professionals
Applies to ascorbic acid: compounding powder, injectable solution, oral capsule, oral gum, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release
Renal
Renal side effects have included oxalate and urate kidney stones.[Ref]
Hyperoxaluria appears to be dose-related.[Ref]
Nervous system
Migraine headache has been reported with a daily dose of 6 grams.
The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.[Ref]
Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.[Ref]
Other
Conditional scurvy is reported to occur following excessive doses of ascorbic acid (the active ingredient contained in Cemill 1000) over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.[Ref]
Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.[Ref]
Gastrointestinal
Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.[Ref]
Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.
Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.[Ref]
Hematologic
The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.[Ref]
Hematologic side effects have included hemolysis.[Ref]
Local
Local side effects have included transient mild soreness at the site of injection.[Ref]
Some side effects of Cemill 1000 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.