Centany AT Kit

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

An overdose of mupirocin topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid getting this medicine in your eyes, mouth, or nose. A separate product called mupirocin nasal is made for use in the nose. Mupirocin topical is for use only on the skin.

Avoid using other medications on the areas you treat with mupirocin topical unless your doctor tells you to.

It is not likely that other drugs you take orally or inject will have an effect on topically applied mupirocin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Applies to mupirocin topical: compounding powder, nasal ointment, topical cream, topical kit, topical ointment

Dermatologic

Nasal Ointment: Cutaneous hypersensitivity reactions have been reported very rarely during postmarketing experience.

Topical Ointment: Cutaneous sensitization reactions to the active component or ointment base have been reported.[Ref]

Nasal Ointment:
-Uncommon (0.1% to 1%): Pruritus/itching
-Frequency not reported: Rash
-Postmarketing reports: Cutaneous hypersensitivity reactions

Topical Cream:
-Common (1% to 10%): Rash, pruritus, cutaneous hypersensitivity reactions
-Frequency not reported: Dry skin, erythema, cellulitis, dermatitis, hives

Topical Ointment:
-Common (1% to 10%): Pruritus/itching, erythema, dry skin/dryness
-Uncommon (0.1% to 1%): Contact dermatitis, furunculosis, exfoliative dermatitis, rash, cutaneous sensitization reactions[Ref]

Gastrointestinal

Frequency not reported: Clostridium difficile-associated diarrhea

Nasal Ointment:
-Frequency not reported: Diarrhea, dry mouth, nausea

Topical Cream:
-Common (1% to 10%): Diarrhea, nausea
-Frequency not reported: Abdominal pain, ulcerative stomatitis

Topical Ointment:
-Frequency not reported: Nausea[Ref]

Hypersensitivity

Postmarketing reports: Systemic allergic reactions (e.g., anaphylaxis, generalized rash, urticaria, angioedema)[Ref]

Systemic allergic reactions have been reported during postmarketing experience very rarely.[Ref]

Local

Nasal Ointment:
-Common (1% to 10%): Burning, irritation, tingling, itching, stinging, soreness, facial pain over maxillae

Topical Cream:
-Common (1% to 10%): Application site reactions, application site burning, application site hypersensitivity reactions (including urticaria, pruritus, erythema, burning sensation, contact dermatitis, rash)

Topical Ointment:
-Common (1% to 10%): Burning, stinging, pain/swelling at application site, dryness, itching, erythema
-Frequency not reported: Increased exudate, application site reactions[Ref]

Nervous system

Nasal Ointment:
-Common (1% to 10%): Taste perversion, headache

Topical Cream:
-Common (1% to 10%): Headache
-Frequency not reported: Dizziness[Ref]

Ocular

Nasal Ointment:
-Common (1% to 10%): Conjunctivitis
-Frequency not reported: Blepharitis, burning, tearing[Ref]

Other

Nasal Ointment:
-Common (1% to 10%): Burning/stinging
-Frequency not reported: Ear pain

Topical Cream:
-Frequency not reported: Bleeding or pain secondary to eczema, secondary wound infection

Topical Ointment:
-Common (1% to 10%): Burning/stinging/pain
-Rare (0.01% to 0.1%): Systemic reactions (not otherwise specified)
-Frequency not reported: Tenderness, swelling, increased exudate[Ref]

Respiratory

Nasal Ointment:
-Common (1% to 10%): Postnasal drip, sinusitis, rhinitis, respiratory disorder (including upper respiratory tract congestion), pharyngitis, cough
-Uncommon (0.1% to 1%): Nasal mucosa reactions
-Frequency not reported: Epistaxis[Ref]

Some side effects of Centany AT Kit may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

12 years or older:
Nasal ointment: Apply about one-half of the tube contents into 1 nostril and the other half into the other nostril twice a day (morning and evening).
Duration of therapy: 5 days

Use: For the eradication of nasal colonization with MRSA in patients and healthcare workers as part of a comprehensive infection control program to reduce risk of MRSA infection among high-risk patients during institutional outbreaks of MRSA infections