Axicabtagene Ciloleucel (Intravenous Route)

Name: Axicabtagene Ciloleucel (Intravenous Route)

Descriptions

Axicabtagene ciloleucel injection is used to treat large B-cell lymphoma (including diffuse large B-cell lymphoma [DLBCL], primary mediastinal large B-cell lymphoma, high grade B-cell lymphoma, or DLBCL from follicular lymphoma) that has come back or after 2 or more lines of treatment did not work well.

Axicabtagene ciloleucel injection is an antineoplastic (cancer) medicine that is made from your own white blood cells, which have been modified to recognize and attack your cancer cells. Before you begin treatment, talk to your doctor about the benefits of this medicine as well as the possible risks of receiving it.

This medicine is available only under a restricted distribution program called Yescarta™ REMS (Risk Evaluation and Mitigation Strategy) Program.

This product is available in the following dosage forms:

  • Suspension

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of axicabtagene ciloleucel injection in the pediatric population. Safety and efficacy have not been established.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart problems or
  • Heart rhythm problems (eg, arrhythmia, tachycardia) or
  • Hypotension (low blood pressure) or
  • Infections (including hepatitis B), active or history of or
  • Kidney disease or
  • Lung or breathing problems or
  • Seizures, history of—Use with caution. May cause side effects to become worse.
(web3)