Benznidazole (Oral Route)

Benznidazole is used to treat Chagas disease (American trypanosomiasis) in children 2 to 12 years of age.

Chagas disease is a potentially life-threatening disease caused by the protozoan parasite, Trypanosoma cruzi, also known as "kissing bug". It can be transmitted by eating food contaminated with the parasite's feces or urine, blood transfusion from infected donors, organ transplant using organs from infected donors, or during pregnancy or childbirth.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of benznidazole in children 2 to 12 years of age. Safety and efficacy have not been established in children younger than 2 years of age and older than 12 years of age.

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Capecitabine
• Cholera Vaccine, Live
• Doxifluridine
• Fluorouracil
• Tegafur

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.