Tyvaso inhalation

Treprostinil dilates (widens) the arteries and decreases the amount of blood clotting platelets in your body. These effects lower blood pressure in the pulmonary artery that leads from the heart to the lungs.

Treprostinil is used to treat pulmonary arterial hypertension (PAH). This medicine improves your ability to exercise and can help prevent your condition from getting worse.

Treprostinil may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

You should not use treprostinil if you are allergic to it.

To make sure treprostinil inhalation is safe for you, tell your doctor if you have:

• asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;

• an infection in your lungs, including pneumonia;

• kidney disease;

• liver disease;

• low blood pressure;

• a bleeding or blood clotting disorder;

• if you take a blood thinner (warfarin, Coumadin, Jantoven); or

• if you take medicine to treat high blood pressure (hypertension).

Treprostinil is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether treprostinil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.

Notes

Do not share this medication with others.

Laboratory and/or medical tests (such as blood pressure) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Once the foil pack is opened, the ampules should be used within 7 days. After an ampule has been opened, discard any unused solution at the end of the day. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised July 2016. Copyright(c) 2016 First Databank, Inc.

Tyvaso (treprostinil) dilates (widens) the arteries and decreases the amount of blood clotting platelets in your body. These effects lower blood pressure in the pulmonary artery that leads from the heart to the lungs.

Tyvaso is used to treat pulmonary arterial hypertension (PAH). This medicine improves your ability to exercise and can help prevent your condition from getting worse.

Tyvaso may also be used for purposes not listed in this medication guide.

Before using Tyvaso, tell your doctor if you have a breathing disorder such as asthma or COPD (chronic obstructive pulmonary disease), an infection in your lungs (including pneumonia), low blood pressure, liver or kidney disease, or a bleeding or blood clotting disorder.

Tyvaso inhalation should be used only with the inhalation system. The inhalation system comes with patient instructions for safe and effective use. Do not use the medication at home if you do not fully understand how to use the inhalation system and properly clean it daily. Ask your doctor or pharmacist if you have any questions.

Use Tyvaso exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

This medicine should be used only with a Tyvaso inhalation system. The inhalation system comes with patient instructions for safe and effective use. Do not use this medicine at home if you do not fully understand how to use the inhalation system and properly clean it daily. Ask your doctor or pharmacist if you have any questions.

Tyvaso inhalation is usually given 4 times per day at evenly spaced intervals during waking hours. Each time you use the medicine, you will inhale up to 9 breaths of the medication. Follow your doctor's instructions.

Do not mix other inhalation medicines with Tyvaso in the inhalation system.

Wash your hands before preparing your doses in the inhalation system.

Before your first dose of each day, twist off the top of one ampule and empty the contents into the medicine cup of the inhalation system. One ampule of Tyvaso inhalation contains enough medicine for all 4 of a day's doses.

To keep the medicine in the cup from spilling, store the inhalation system upright and tightly capped with the plugs when not in use.

At the end of the day after your last dose, empty and rinse out the medicine cup, even if there is still some medicine left in it.

The effects of Tyvaso inhalation will lessen over time between doses. Talk with your doctor if you need to time your dosing around any planned activities.

Do not use more than 9 breaths per treatment session, 4 times per day.

Use Tyvaso regularly to get the most benefit. You should not reduce your dose or stop using this medicine suddenly. Stopping suddenly may make your condition worse. Get your prescription refilled before you run out of medicine completely. Make sure you have a backup inhalation system available so as not to interrupt your treatment if one system stops working.

Call your doctor if your symptoms do not improve, or if they get worse while using Tyvaso inhalation.

Store the ampules in their foil pouch at room temperature away from moisture, heat, and light. Once you have opened a foil pouch, the ampules in it should be used within 7 days.

Any Tyvaso placed into the medicine cup of the inhalation system must be used within 24 hours. Throw away any unused medicine at the end of the day after your last dose.

Other drugs may interact with treprostinil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.