Name: Tyzine

What are some things I need to know or do while I take Tyzine?

  • Tell all of your health care providers that you take Tyzine. This includes your doctors, nurses, pharmacists, and dentists.
  • If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
  • Do not use more than what your doctor told you to use. Do not use more often or longer than what you were told. Doing any of these things may raise the chance of very bad side effects.
  • If you use this medicine too often, your stuffy nose may get worse.
  • This medicine may cause harm if swallowed or if too much is used. The chance is higher in children. If Tyzine is swallowed or too much is used, call a doctor or poison control center right away.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Tyzine) best taken?

Use Tyzine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Follow how to use as you have been told by the doctor or read the package insert.
  • Do not take this medicine by mouth. Use in your nose only. Keep out of your mouth and eyes (may burn).
  • Blow your nose before use.
  • Do not tilt your head back before using Tyzine.

What do I do if I miss a dose?

  • If you use this medicine on a regular basis, use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Many times Tyzine (tetrahydrozoline (nasal)) is taken on an as needed basis. Do not take more often than told by the doctor.
  • Do not use 2 doses at the same time or extra doses.

How do I store and/or throw out Tyzine?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Do not use if solution changes color.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Tyzine Description

Tyzine® Nasal Solution contains tetrahydrozoline hydrochloride, 2-(1,2,3,4-Tetrahydro-1, naphthyl)-2-imidazoline monohydrochloride, as a nasal decongestant. The chemical structure is:

Nasal Solution is available for topical nasal application as 0.1% nasal solution and as 0.05% pediatric nasal drops. The nasal solution is a solution of tetrahydrozoline hydrochloride in water, with sodium chloride, sodium citrate, edetate disodium, and benzalkonium chloride, with hydrochloric acid to adjust to the pH.

Indications and Usage for Tyzine

Tyzine® Nasal Solution is indicated for decongestion of nasal and nasopharyngeal mucosa.


NDC 0482-4770-15

Rx Only



(tetrahydrozoline hydrochloride)


15 mL (1/2 FL. OZ.)


For the Consumer

Applies to tetrahydrozoline nasal: nasal solution

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Chest pain or pressure, a fast heartbeat, or passing out.
  • A heartbeat that does not feel normal.
  • Shakiness.
  • Very bad headache.
  • Very bad dizziness.
  • Pale skin.
  • Sweating a lot.
  • Feeling sleepy.
  • Feeling very tired or weak.
  • Not able to sleep.