Tussin CF

Name: Tussin CF

What is Tussin CF (dextromethorphan, guaifenesin, and phenylephrine)?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dextromethorphan, guaifenesin, and phenylephrine is a combination medicine used to treat cough, stuffy nose, sinus congestion and chest congestion caused by allergies, the common cold, or the flu.

There are many brands and forms of this medicine available. Not all brands are listed on this leaflet.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan, guaifenesin, and phenylephrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about this medicine?

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

What should I discuss with my healthcare provider before taking this medicine?

You should not use this medicine if you are allergic to dextromethorphan, guaifenesin, or phenylephrine.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take dextromethorphan, guaifenesin, and phenylephrine if you have:

  • high blood pressure or coronary artery disease;

  • diabetes;

  • glaucoma;

  • epilepsy or other seizure disorder;

  • enlarged prostate or urination problems;

  • pheochromocytoma (an adrenal gland tumor); or

  • cough with mucus, or cough caused by emphysema or chronic bronchitis.

It is not known whether dextromethorphan, guaifenesin, and phenylephrine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

This medicine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What should I avoid while taking this medicine?

This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of this medicine.

Ask a doctor or pharmacist before using any other cold, cough, or allergy medicine. Dextromethorphan, guaifenesin, and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains a decongestant, expectorant, or cough suppressant.

For the Consumer

Applies to dextromethorphan / guaifenesin / phenylephrine: oral liquid, oral syrup, oral tablet

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