Topamax Sprinkle

Topamax Sprinkle is a seizure medicine, also called an anticonvulsant. This medicine is used to treat seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old.

Extended-release Topamax Sprinkle has a higher minimum age (at least 10 years old) when used as the child's only seizure medicine.

Some brands of Topamax Sprinkle are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun.

Topamax Sprinkle may also be used for purposes not listed in this medication guide.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, agitation, depression, double vision, thinking problems, problems with speech or coordination, fainting, and seizure (convulsions).

Do not drink alcohol. Dangerous side effects or increased seizures may occur.

Avoid becoming overheated or dehydrated in hot weather. Topamax Sprinkle can decrease sweating and increase body temperature, leading to life-threatening dehydration (especially in children).

Ketogenic or "ketosis" diets that are high in fat and low in carbohydrates can increase the risk of kidney stones. Avoid the use of such diets while you are taking Topamax Sprinkle.

Topamax Sprinkle may cause blurred vision or impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.

Also avoid activities that could be dangerous if you have an unexpected seizure, such as swimming or climbing in high places.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening mood symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

• vision problems, eye pain or redness, sudden vision loss (can be permanent if not treated quickly);

• confusion, problems with thinking or memory, trouble concentrating, problems with speech;

• dehydration symptoms--decreased sweating, high fever, hot and dry skin;

• signs of a kidney stone--severe pain in your side or lower back, painful or difficult urination;

• signs of too much acid in your blood--irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath; or

• signs of too much ammonia in your blood--vomiting, unexplained weakness, feeling like you might pass out.

Common side effects may include:

• fever, weight loss;

• numbness or tingling in your arms and legs;

• flushing (warmth, redness, or tingly feeling);

• headache, dizziness, drowsiness, tired feeling, slow reactions;

• mood problems, feeling nervous;

• nausea, diarrhea, stomach pain, loss of appetite, indigestion;

• cold symptoms such as stuffy nose, sneezing, sore throat; or

• changes in your sense of taste.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Using Topamax Sprinkle with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression.

Tell your doctor about all your other medicines, especially:

• lithium;

• metformin;

• birth control pills;

• glaucoma medication; or

• other seizure medicines--carbamazepine, divalproex sodium, phenytoin, valproic acid, or zonisamide.

This list is not complete. Other drugs may affect Topamax Sprinkle, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.