Maxzide-25

• If you have an allergy to hydrochlorothiazide, triamterene, or any other part of this medicine.
• If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you have a sulfa (sulfonamide) allergy, talk with your doctor.
• If you have any of these health problems: High potassium levels or kidney disease.
• If you are not able to pass urine.
• If you are taking dofetilide.
• If you are taking any of these drugs: Amiloride, spironolactone, or another drug that has triamterene in it.
• If you are taking a salt substitute that has potassium, potassium-sparing diuretics, or potassium, talk with your doctor.
• If you are breast-feeding. Do not breast-feed while you take Maxzide-25.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Maxzide-25 with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

• Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how Maxzide-25 affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
• If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
• Check your blood sugar as you have been told by your doctor.
• Have your blood pressure checked often. Talk with your doctor.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine.
• If you are on a low-salt or salt-free diet, talk with your doctor.
• Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
• Watch for gout attacks.
• If you have lupus, Maxzide-25 can make your lupus active or get worse. Tell your doctor right away if you get any new or worse signs.
• You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
• Tell your doctor if you have too much sweat, fluid loss, throwing up, or loose stools. This may lead to low blood pressure.
• If you are 65 or older, use this medicine with care. You could have more side effects.
• Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Maxzide-25 while you are pregnant.

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with or without food. Take with food if it causes an upset stomach.
• This medicine may cause you to pass urine more often. To keep from having sleep problems, try to take before 6 pm.
• To gain the most benefit, do not miss doses.
• Keep taking Maxzide-25 as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Maxzide-25 (hydrochlorothiazide and triamterene), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Maxzide-25. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Maxzide-25.

Review Date: October 4, 2017

Applies to hydrochlorothiazide / triamterene: oral capsule, oral tablet

Along with its needed effects, hydrochlorothiazide / triamterene may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide / triamterene:

• Abdominal or stomach pain
• agitation
• back or leg pains
• black, tarry stools
• bleeding gums
• blisters, hives, or itching
• bloating
• blood in the urine or stools
• blue lips and fingernails
• blurred vision
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain
• chills
• clay-colored stools
• cloudy urine
• cold sweats
• coma
• confusion
• constipation
• convulsions
• cough or hoarseness
• coughing that sometimes produces a pink frothy sputum
• dark urine
• decreased urine output
• depression
• difficult, fast, noisy breathing, sometimes with wheezing
• difficulty swallowing
• dizziness, faintness, or lightheadedness when getting up from lying or sitting position
• drowsiness
• dry mouth
• fast, slow, or irregular heartbeat
• fever with or without chills
• flushed, dry skin
• fruit-like breath odor
• general body swelling
• general feeling of discomfort, illness, or weakness
• greatly decreased frequency of urination or amount of urine
• headache
• hostility
• incoherent speech
• increased hunger
• increased sweating
• increased thirst
• increased urination
• indigestion
• irritability
• joint pain, stiffness, or swelling
• lethargy
• loss of appetite
• loss of consciousness
• lower back or side pain
• metallic taste
• mood changes
• muscle pain, cramps, weakness, or twitching
• nausea or vomiting
• nervousness
• nosebleeds
• numbness or tingling in the hands, feet, or lips
• pain in the groin or genitals
• painful or difficult urination
• pains in the stomach, side, or abdomen, possibly radiating to the back
• pale skin
• pinpoint red or purple spots on the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rapid weight gain
• seizures
• sharp back pain just below the ribs
• shortness of breath
• skin rash
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• stomachache
• stupor
• sugar in the urine
• swelling of the face, ankles, hands, feet, or lower legs
• swollen or painful glands
• thickening of bronchial secretions
• tightness in the chest
• troubled breathing
• unexplained weight loss
• unpleasant breath odor
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting of blood
• weak pulse
• weakness or heaviness of the legs
• wheezing
• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydrochlorothiazide / triamterene:

• Face is warm or hot to touch
• frequent urination
• increased volume of pale, dilute urine
• loss of strength or energy
• pain or weakness in the hands or feet
• redness to face
• reflexes are unusually strong
• trembling

Some side effects of hydrochlorothiazide / triamterene may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Decreased interest in sexual intercourse
• feeling of constant movement of self or surroundings
• inability to have or keep an erection
• increased sensitivity of the skin to sunlight
• loss in sexual ability, desire, drive, or performance
• redness or other discoloration of the skin
• sensation of spinning
• severe sunburn
• welts