Mandelamine

Name: Mandelamine

Mandelamine Overview

Mandelamine is a brand name medication included in a group of medications called OTHER ANTIBACTERIALS. For more information about Mandelamine see its generic Methenamine

Commonly used brand name(s)

In the U.S.

  • Hiprex
  • Mandelamine
  • Urex

In Canada

  • Urasal

Available Dosage Forms:

  • Tablet
  • Suspension
  • Tablet, Enteric Coated

Therapeutic Class: Antiseptic

Uses For Mandelamine

Methenamine belongs to the family of medicines called anti-infectives. It is used to help prevent and treat infections of the urinary tract. Methenamine is available only with your doctor's prescription.

Usual Adult Dose for Pyelonephritis

Hippurate: 1 g orally twice a day (morning and night)
Mandelate: 1 g orally 4 times a day (after each meal and at bedtime)

Uses:
-Hippurate: For prophylactic or suppressive treatment of frequently recurring urinary tract infections (UTIs) when long-term therapy deemed necessary
-Mandelate: For the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic UTIs; for infected residual urine due to some neurologic diseases

Usual Pediatric Dose for Cystitis

Hippurate:
6 to 12 years: 0.5 to 1 g orally twice a day (morning and night)
13 years or older: 1 g orally twice a day (morning and night)

Mandelate:
6 to 12 years: 0.5 g orally 4 times a day (after each meal and at bedtime)
13 years or older: 1 g orally 4 times a day (after each meal and at bedtime)

Uses:
-Hippurate: For prophylactic or suppressive treatment of frequently recurring UTIs when long-term therapy deemed necessary
-Mandelate: For the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic UTIs; for infected residual urine due to some neurologic diseases

Usual Pediatric Dose for Cystitis Prophylaxis

Hippurate:
6 to 12 years: 0.5 to 1 g orally twice a day (morning and night)
13 years or older: 1 g orally twice a day (morning and night)

Mandelate:
6 to 12 years: 0.5 g orally 4 times a day (after each meal and at bedtime)
13 years or older: 1 g orally 4 times a day (after each meal and at bedtime)

Uses:
-Hippurate: For prophylactic or suppressive treatment of frequently recurring UTIs when long-term therapy deemed necessary
-Mandelate: For the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic UTIs; for infected residual urine due to some neurologic diseases

Usual Pediatric Dose for Pyelonephritis

Hippurate:
6 to 12 years: 0.5 to 1 g orally twice a day (morning and night)
13 years or older: 1 g orally twice a day (morning and night)

Mandelate:
6 to 12 years: 0.5 g orally 4 times a day (after each meal and at bedtime)
13 years or older: 1 g orally 4 times a day (after each meal and at bedtime)

Uses:
-Hippurate: For prophylactic or suppressive treatment of frequently recurring UTIs when long-term therapy deemed necessary
-Mandelate: For the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic UTIs; for infected residual urine due to some neurologic diseases

Usual Pediatric Dose for Urinary Tract Infection

Hippurate:
6 to 12 years: 0.5 to 1 g orally twice a day (morning and night)
13 years or older: 1 g orally twice a day (morning and night)

Mandelate:
6 to 12 years: 0.5 g orally 4 times a day (after each meal and at bedtime)
13 years or older: 1 g orally 4 times a day (after each meal and at bedtime)

Uses:
-Hippurate: For prophylactic or suppressive treatment of frequently recurring UTIs when long-term therapy deemed necessary
-Mandelate: For the suppression or elimination of bacteriuria associated with pyelonephritis, cystitis, and other chronic UTIs; for infected residual urine due to some neurologic diseases

Renal Dose Adjustments

Renal dysfunction: Contraindicated

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

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