Lotrimin AF

The most commonly noted side effects associated with clotrimazole include:

• local redness,
• stinging,
• blistering,
• peeling,
• swelling,
• itching,
• hives, or
• burning at the area of application.

Other side effects include nausea and vomiting, which may be caused by the oral forms.

Miconazole is a prescription antifungal medicine used in adults to treat fungal (yeast) infections of the mouth and the throat.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Grapefruit and grapefruit juice may interact with miconazole and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

The recommended dosing schedule for miconazole is the application of one 50 mg buccal tablet to the upper gum region once daily for 14 consecutive days.

• Store miconazole between 68 to 77 °F (20 to 25°C)
• Keep miconazole dry
• Keep miconazole and all medicine out of the reach of children

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Miconazole topical is for use only on the skin. Do not use this medicine on open wounds.

Miconazole topical is not for use in the vagina or rectum.

Wash your hands before and after using this medication, unless you are treating a skin condition on your hands.

Clean and dry the affected area. Apply the cream, lotion, spray, or powder once or twice daily as directed for 2 to 4 weeks.

Do not cover the treated skin area unless your doctor tells you to. A light cotton-gauze dressing may be used to protect clothing.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine.

Call your doctor if the infection does not clear up in 2 weeks (or 4 weeks for athlete's foot), or if it appears to get worse.

Store at room temperature away from moisture and heat. Keep the tube tightly closed when not in use.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using miconazole topical and call your doctor at once if you have:

• severe blistering, redness, or irritation of treated skin.

Common side effects may include:

• itching, peeling, or dry skin.

Although the risk of serious side effects is low when miconazole topical is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream, including:

• dry mouth, sore tongue, tooth pain, red or swollen gums;

• altered sense of taste;

• nausea, diarrhea; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

It is not likely that other drugs you take orally or inject will have an effect on topically applied miconazole. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Applies to miconazole topical: compounding powder, topical cream, topical gel, topical liquid, topical lotion, topical ointment, topical powder, topical spray, topical tincture, vaginal cream, vaginal cream with applicator, vaginal kit, vaginal suppository, vaginal tampon

Local

Local side effects have been reported frequently with topical miconazole therapy. When administered intravaginally or topically, itching, burning and rash have been reported. Contact dermatitis, confirmed by patch testing, has been reported.[Ref]

Nervous system

Nervous system side effects have rarely included headache.[Ref]

Genitourinary

Genitourinary side effects have included cramping, pain, and bleeding with the intravaginal use of miconazole.[Ref]

Some side effects of Lotrimin AF Athlete's Foot Powder may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.