Lumizyme injection

Alglucosidase alfa contains an enzyme that naturally occurs in the body in healthy people. Some people lack this enzyme because of a genetic disorder. Alglucosidase alfa helps replace this missing enzyme in such people.

Alglucosidase alfa is used to treat a glycogen storage disorder called Pompe disease, (also called GAA deficiency) in adults and children who are at least 8 years old.

Alglucosidase alfa may also be used for purposes not listed in this medication guide.

Other drugs may interact with alglucosidase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Lumizyme is injected into a vein through an IV. A healthcare provider will give you this injection. Lumizyme must be given slowly, and the IV infusion can take up to 4 hours to complete.

This medicine is usually given once every 2 weeks.

Before each injection, tell your doctor if you have recently been sick with a cold, flu, or other illness.

If you need surgery, tell the surgeon ahead of time that you are using Lumizyme.

Lumizyme can have long lasting effects on your body. Your blood will need to be tested every 3 months for 2 years and then once every year after that.

Usual Adult Dose for Pompe disease:

20 mg/kg via IV infusion every 2 weeks

Comments:
-Total volume of infusion is determined by patient's body weight and should be infused over about 4 hours.

Usual Pediatric Dose of Lumizyme for Pompe disease:

20 mg/kg via IV infusion every 2 weeks

Comments:
-Total volume of infusion is determined by body weight and should be infused over about 4 hours.

Other drugs may interact with alglucosidase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Call your doctor for instructions if you miss an appointment for your Lumizyme injection.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Common side effects of Lumizyme include: bradycardia, cough, fever, infusion related reaction, oxygen desaturation, skin rash, tachycardia, tachypnea, urticaria, vomiting, and flushing. See below for a comprehensive list of adverse effects.