Iodine

Name: Iodine

Warnings

Contraindications

Hypersensitivity to drug or components

Cautions

Excessive iodine may cause hypothyroidism by feedback inhibition of thyroid hormone production & conversion of triiodothyronine (T3) to less active thyroxine (T4)

Use caution in patients with renal impairment

Iodine and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Iodine falls into category D:

It has been shown that use of Iodine in pregnant women caused some babies to be born with problems. However, in some serious situations, the benefit of using this medication may be greater than the risk of harm to the baby.

Introduction

Nonmetallic element; a topical anti-infective agent.a b c e f

Iodine Pharmacokinetics

Absorption

Bioavailability

Absorbed systemically following application of cadexomer iodine pad or gel.h i

Duration

Following application of cadexomer pad or gel, iodine released slowly over 24–72 hours (depending on amount of wound exudate) from cadexomer beads as they absorb fluid.h i

Distribution

Extent

Iodide readily crosses the placenta and is distributed into milk.d

Stability

Storage

Topical

Solution and Tincture

Tight, light-resistant containers at ≤35°C.a

Cadexomer Gel and Pad

15–30°C.h i

Index Terms

  • Iodoflex
  • Iodosorb

Administration

Topical: Iodosorb®: Apply 1/8" to 1/4" thickness to dry sterile gauze, then place prepared gauze onto clean wound. Change dressing when gel changes color from brown to yellow/gray (~3 times/week). Remove with sterile water, saline, or wound cleanser; gently blot fluid from surface leaving wound slightly moist before reapplying gel.

Storage

Store at room temperature.

Test Interactions

Large amounts from excessive absorption may alter thyroid function tests.

Interactions

Consult your pharmacist.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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