Gamunex-C

• It is used to stop or lower the harshness of other infections in people with a weak immune system.
• It is used to treat immune thrombocytopenia (ITP).
• It is used treat chronic inflammatory demyelinating polyneuropathy (CIDP).
• It is used to treat multifocal muscle neuropathy.
• It may be given to you for other reasons. Talk with the doctor.

Gamunex-C is an immune globulin injection (human) 10% liquid that is indicated for the treatment of:

 Primary Humoral Immunodeficiency (PI)

Gamunex-C is indicated as replacement therapy of primary humoral immunodeficiency. This includes, but is not limited to, congenital agammaglobulinemia, common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.(2-5)

Idiopathic Thrombocytopenic Purpura (ITP)

Gamunex-C is indicated for the treatment of patients with Idiopathic Thrombocytopenic Purpura to raise platelet counts to prevent bleeding or to allow a patient with ITP to undergo surgery.(6,7)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Gamunex-C is indicated for the treatment of CIDP to improve neuromuscular disability and impairment and for maintenance therapy to prevent relapse.

Gamunex-C may be diluted with 5% dextrose in water (D5/W). Do not dilute with saline. Admixtures of Gamunex-C with other drugs and intravenous solutions have not been evaluated. It is recommended that Gamunex-C be administered separately from other drugs or medications which the patient may be receiving. The product should not be mixed with IGIVs from other manufacturers.

The infusion line may be flushed before and after administration of Gamunex-C with 5% dextrose in water (D5/W) or 0.9% sodium chloride for injection.

Avoid simultaneous administration of Gamunex-C and Heparin through a single lumen delivery device due to Gamunex-C, Heparin incompatibilities. Flush Heparin Lock (Hep-Lock) through which Gamunex-C was administered with 5% dextrose in water (D5/W) or 0.9% sodium chloride for injection, and do not flush with Heparin.

Various passively transferred antibodies in immunoglobulin preparations can confound the results of serological testing.

Passive transfer of antibodies may transiently interfere with the immune response to live virus vaccines such as measles, mumps, rubella and varicella. Inform the immunizing physician of recent therapy with Gamunex-C so that appropriate measures may be taken. (see Patient Counseling Information [17])

Gamunex-C is supplied in single-use, tamper evident vials (shrink band) containing the labeled amount of functionally active IgG. The four larger vial size labels incorporate integrated hangers. The components used in the packaging for Gamunex-C are latex-free.


Gamunex-C is supplied in the following sizes:

• DO NOT FREEZE
• Gamunex-C may be stored for 36 months at 2-8°C (36-46°F) from the date of manufacture, AND product may be stored at temperatures not to exceed 25°C (77°F) for up to 6 months anytime during the 36 month shelf life, after which the product must be immediately used or discarded.
• Do not use after expiration date.