Folvite
Name: Folvite
- Folvite side effects
- Folvite serious side effects
- Folvite dosage
- Folvite drug
- Folvite missed dose
- Folvite uses
- Folvite 1 mg
- Folvite action
- Folvite injection
Precautions
Drug interactions
Missed dose
Dosing & Uses
Dosage Forms & Strengths
tablet
- 400mcg
- 800mcg
- 1mg
injectable solution
- 5mg/mL
Nutritional Supplementation
Recommended daily allowance (RDA)
Males: 400 mcg/day PO
Females: 400-800 mcg/day PO
Pregnant women: 600 mcg/day PO
Nursing women: 500 mcg/day PO
Upper limit: 1 mg/day PO
Neural Tube Defects Prophylaxis
Females of childbearing potential: 400 mcg/day PO
Pregnancy women: 600 mcg/day PO
Females with high risk or family history of neural tube defects: 4 mg/day PO
Folic Acid Deficiency
0.4-1 mg PO/IV/IM/SC once daily
Methanol Toxicity
50-75 mg IV q4hr for 24 hr
Methotrexate Toxicity Prophylaxis (Off-label)
1 mg PO qDay; may increase up to 5 mg/day if toxicity emerges
Dosage Forms & Strengths
tablet
- 400mcg
- 800mcg
- 1mg
injectable solution
- 5mg/mL
Nutritional Supplementation
RDA
0-6 months: 65 mcg/day PO
7-12 months: 80 mcg/day PO
1-4 years: 150 mcg/day PO
4-9 years: 200 mcg/day PO
9-14 years: 300 mcg/day PO
14-18 years: 400 mcg/day PO
Upper limit: 1-4 years, 300 mcg/day PO; 4-8 years, 400 mcg/day PO
Folic Acid Deficiency
Infants: 15 mcg/kg/day or 50 mcg/day IV/PO/IM/SC
1-10 years: 1 mg/day IV/PO/IM/SC initially, then 0.1-0.4 mg/day
Methanol Toxicity
1 mg/kg IV q4hr for 24 hr
Pharmacology
Mechanism of Action
Necessary for formation of coenzymes in metabolic systems (purine and pyrimidine synthesis required for maintenance in erythropoiesis); stimulates platelet production in folate deficiency anemia
Enhances elimination of formic acid in methanol toxicity via provision of coenzyme to folate dehydrogenase
Absorption
Absorbed in proximal part of small intestine
Onset: PO, 0.5-1 hr
Metabolism
Metabolized in liver
Elimination
Excretion: Urine
Administration
IV/IM/SC Administration
Administer by IV/IM/SC injection only when PO administration is not feasible or when malabsorption is suspected
Most individuals with malabsorption can absorb oral folic acid
For IM use, administer by deep injection
Side effects
Allergic sensitization has been reported following both oral and parenteral administration of folic acid.
Related health
- Anemia