Guanfacine-oral

Name: Guanfacine-oral

What is guanfacine-oral, and how does it work (mechanism of action)?

Guanfacine is an oral, centrally-acting alpha 2A adrenergic receptor agonist. It is available in two different formulations, Tenex immediate release tablets and Intuniv extended release tablets. Tenex is used alone or in combination with other medications for the treatment of hypertension (high blood pressure). Guanfacine reduces blood pressure by reducing the resistance of blood flow in the blood vessels, and by decreasing heart rate.

Intuniv (guanfacine extended release) is used alone or in combination with other medications for the treatment of attention deficit hyperactivity disorder (ADHD). The exact mechanism of action of guanfacine in ADHD is unknown. Extended release guanfacine is effective for the treatment of ADHD in children and adolescents between the ages of 6 to 17 in clinical trials lasting 8 weeks.

Guanfacine was approved by the US Food and Drug Administration (FDA) in 1986.

What brand names are available for guanfacine-oral?

Intuniv, Tenex

Is guanfacine-oral available as a generic drug?

GENERIC AVAILABLE: Yes

What are the side effects of guanfacine-oral?

The most common side effects associated with guanfacine treatment are

  • tiredness,
  • sleepiness,
  • trouble sleeping,
  • nausea,
  • low blood pressure,
  • stomach pain, and
  • dizziness.

Other important side effects that are rare, but serious, are:

  • hair loss,
  • memory impairment,
  • heart failure,
  • depression,
  • seizures,
  • skin problems,
  • difficulty swallowing,
  • edema,
  • hallucinations,
  • hypersensitivity or
  • allergic
  • reactions,
  • mania,
  • heart attack,
  • rebound hypertension,
  • kidney failure,
  • rapid heartbeat, and
  • visual disturbance.

From

Heart Health Resources
  • Hypertension Can Hurt Your Eyes
  • Your Medications and Hearing Loss
  • Caring for Your New Kidney
Featured Centers
  • 13 Best Quit-Smoking Tips Ever
  • What Stress Does to Your Mouth
  • Healthy Home: To Buy or Not to Buy Organic?
Health Solutions From Our Sponsors
  • Frequent Constipation?
  • Greater Food Accessibility
Reviewed on 9/11/2015 References REFERENCE: FDA Prescribing Information.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, severe dizziness, severe tiredness, very slow heartbeat, pinpoint pupils.

Notes

Do not share this medication with others.

Because this drug can affect your blood pressure and heart rate, your doctor should check your blood pressure and heart rate regularly while you are taking this medication.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up. If you miss more than 2 doses in a row, call your doctor to get a new dosing schedule.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised July 2017. Copyright(c) 2017 First Databank, Inc.

(web3)