Hyoscyamine-sublingual

Name: Hyoscyamine-sublingual

What is hyoscyamine-sublingual, and how does it work (mechanism of action)?

  • Hyoscyamine is an anticholinergic drug used for treating irritable bowel syndrome, peptic ulcer disease, hypermotility of the lower urinary tract, and gastrointestinal disorders. Anticholinergics work by blocking the action of acetylcholine in the brain and at nerves throughout the body. Acetylcholine is a neurotransmitter. Neurotransmitters are chemicals made and released by nerves that travel to nearby nerves or, in the case of acetylcholine, nearby muscles and glands where they attach to receptors on the surface of the nerve, muscle or glandular cells. The attachment of the neurotransmitter can stimulate or inhibit the activity of the receptor-containing cells. Anticholinergic drugs like hyoscyamine affect the function of many organs by preventing acetylcholine from binding to its receptors. Hyoscyamine decreases the activity of muscles in the intestine and lower urinary tract. It reduces the production of sweat, saliva, digestive juices, urine, and tears. It also reduces the production of bronchial secretions.

What brand names are available for hyoscyamine-sublingual?

Levbid, Levsin, Nulev, Anaspaz

Is hyoscyamine-sublingual available as a generic drug?

GENERIC AVAILABLE: Yes

Is hyoscyamine-sublingual safe to take if I'm pregnant or breastfeeding?

  • It is not known whether hyoscyamine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. It should only be given to pregnant women when it is clearly needed.
  • Hyoscyamine is excreted in breast milk.

What else should I know about hyoscyamine-sublingual?

What preparations of hyoscyamine-sublingual are available?
  • Capsules or tablet Extended Release: 0.375 mg.
  • Elixir: 0.125 mg/5 ml.
  • Injections: 0.5 mg/ml.
  • Oral Drops: 0.125 mg/ml.
  • Tablet: 0.125 mg

How should I keep hyoscyamine-sublingual stored?
  • Hyoscyamine should be stored at room temperature between 20 C and 25 C (68 F and 77 F).

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Reviewed on 8/23/2016 References REFERENCE: FDA Prescribing Information
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