Emend Intravenous

In the U.S.

• Emend

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antiemetic

Pharmacologic Class: Fosaprepitant

A nurse or other trained health professional will give you this medicine in a hospital or clinic. This medicine is given through a needle placed in one of your veins. The infusion may take up to 30 minutes.

This medicine is usually given on the first day of your chemotherapy along with other medicines. Fosaprepitant is not for long-term use, but you may need to use this medicine again if you have more chemotherapy in the future.

This medicine comes with a patient information insert. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.

You should not receive this medicine if you are also using pimozide (Orap®). Fosaprepitant may cause serious or life-threatening problems if used together with this medicine.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have itching, hives, a rash, trouble breathing, trouble swallowing, warmth or redness in your face, neck, arms, or upper chest, or any swelling of your hands, face, or mouth while you are receiving this medicine.

If you are also using a blood thinner called warfarin (Coumadin®, Jantoven®), your doctor will need to check your blood after using this medicine.

Birth control pills may not work as well while you are using fosaprepitant. To keep from getting pregnant, use another form of birth control together with your pills during treatment and for one month after your last treatment. Other forms include condoms, a diaphragm, and contraceptive foam or jelly.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Before using fosaprepitant, tell your doctor or pharmacist if you are allergic to it; or to aprepitant; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

No adjustment recommended.

No adjustment recommended.