Elliotts B Solution

Name: Elliotts B Solution

Elliotts B Solution Description

Elliotts B® Solution is a sterile, nonpyrogenic, isotonic solution containing no bacteriostatic preservatives. Elliotts B Solution is a diluent for intrathecal administration of methotrexate sodium and cytarabine.

Each 10 mL of Elliotts B Solution contains:

Sodium Chloride, USP 73 mg
Sodium Bicarbonate, USP 19 mg
Dextrose, USP 8 mg
Magnesium Sulfate • 7H2O, USP 3 mg
Potassium Chloride, USP 3 mg
Calcium Chloride • 2H2O, USP 2 mg
Sodium Phosphate, dibasic • 7H2O, USP 2 mg
Water for Injection, USP qs 10 mL


Concentration of Electrolytes:

Sodium 149 mEq/liter Bicarbonate 22.6 mEq/liter
Potassium 4.0 mEq/liter Chloride 132 mEq/liter
Calcium 2.7 mEq/liter Sulfate 2.4 mEq/liter
Magnesium 2.4 mEq/liter Phosphate 1.5 mEq/liter

The formulae and molecular weights of the ingredients are:

INGREDIENT MOLECULAR
FORMULA
MOLECULAR
WEIGHT
Sodium Chloride NaCl 58.44
Sodium Bicarbonate NaHCO3 84.01
Dextrose C6H12O6 180.16
Magnesium Sulfate • 7H2O Mg2SO4 • 7H2O 246.48
Potassium Chloride KCl 74.55
Calcium Chloride • 2H2O CaCl2 • 2H2O 147.01
Sodium Phosphate, dibasic • 7H2O Na2HPO4 • 7H2O 268.07



The pH of Elliotts B Solution is 6.0-7.5, and the osmolarity is 288 mOsmol per liter (calculated).

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