Drithocreme Topical

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of anthralin in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of anthralin in the elderly with use in other age groups.

Pregnancy

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Skin diseases or problems (other)—Anthralin may make the condition worse

This section provides information on the proper use of a number of products that contain anthralin. It may not be specific to Drithocreme. Please read with care.

Keep this medicine away from the eyes and mucous membranes, such as the mouth and the inside of the nose.

Do not apply this medicine to blistered, raw, or oozing areas of the skin or scalp.

Do not use this medicine on your face or sex organs or in the folds and creases of your skin. If you have any questions about this, check with your doctor.

Use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Anthralin may be used in different ways. In some cases, it is applied at night and allowed to remain on the affected areas overnight, then washed off the next morning or before the next application. In other cases, it may be applied and allowed to remain on the affected areas for a short period of time (usually 10 to 30 minutes), then washed off. (This is called short contact treatment.) Make sure you understand exactly how you are to use this medicine. If you have any questions about this, check with your doctor.

Anthralin may cause irritation of normal skin. If it does, petrolatum may be applied to the skin or scalp around the affected areas for protection.

Apply a thin layer of anthralin to only the affected area of the skin or scalp and rub in gently and well.

Immediately after applying this medicine, wash your hands to remove any medicine that may be on them.

For patients using anthralin for short contact (usually 10 to 30 minutes) treatment:

• After applying anthralin, allow the medicine to remain on the affected area for 10 to 30 minutes or as directed by your doctor. Then remove the medicine by bathing, if the anthralin was applied to the skin, or by shampooing, if it was applied to the scalp.

For patients using the cream form of anthralin for overnight treatment:

• If anthralin cream is applied to the skin, any medicine remaining on the affected areas the next morning should be removed by bathing.
• If anthralin cream is applied to the scalp, shampoo to remove the scales and any medicine remaining on the affected areas from the previous application. Dry the hair and, after parting, rub the cream into the affected areas. Check with your doctor to see when the cream should be removed.

For patients using the ointment form of anthralin for overnight treatment:

• If anthralin ointment is applied to the skin at night, any ointment remaining on the affected areas the next morning should be removed with warm liquid petrolatum followed by bathing.
• If anthralin ointment is applied to the scalp at night, shampoo the next morning to clean the scalp.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For psoriasis:
  • For cream dosage form:
    • Adults—Apply to the dry, affected area(s) of the skin once a day, preferably at night, or as directed by your doctor. Wash medicine off skin at the proper time.
    • Children—Use and dose must be determined by your doctor.
  • For ointment dosage form:
    • Adults—Apply to the dry, affected area(s) of the skin once a day or as directed by your doctor. Wash medicine off skin at the proper time.
    • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Anthralin has been shown to cause tumors in animals. However, there have been no reports of anthralin causing tumors in humans.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Redness or other skin irritation of treated or uninvolved skin not present before use of this medicine

• Skin rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

This medication is used for the treatment of long-term psoriasis. Anthralin is a man-made version of a natural substance found in goa powder, which is from the araroba tree. It works by slowing down the growth of skin cells. This product does not contain a corticosteroid or coal tar. It is not meant to be used for a severe outbreak of psoriasis. Do not use this drug if the skin is inflamed or irritated.

How to use Drithocreme Cream

Exactly follow all directions from your doctor and pharmacist. Learn how to apply the medicine, how long to leave it on the scalp or skin, and how to avoid staining.

This medication is for use on the skin and/or scalp.

To prevent discoloration of fingernails, apply this medication using plastic gloves.

Apply a thin layer to the area with psoriasis, usually once daily. Avoid the normal skin/scalp. Rub in well. If normal skin surrounding the treated areas becomes too irritated, you may cover the normal skin with petroleum jelly to protect it.

To treat the scalp, wash hair first with a shampoo to remove loose scales. Rinse off the shampoo, then apply this medication as directed, only on the psoriasis area.

Follow your doctor's directions for how long to leave the drug on the skin/scalp (usually starting at 10-30 minutes per treatment), then remove the drug. First, rinse with cool-to-lukewarm water (less than 80 degrees F/27 degrees C). Then, if you are treating the scalp, shampoo the scalp, and if you are treating the skin, wash the treated skin by taking a bath or shower using soap and hot water.

After using this medicine, rinse hands right away with lukewarm water, then wash with soap and warm water.

Do not allow the drug to come in contact with eyes, mucous membranes (e.g., lips, mouth, nose), or genital area. If this occurs, flush with plenty of cool-to-lukewarm water. If irritation occurs, contact your doctor right away.

Caution is advised when applying on the areas between toes and fingers, on the face, or in skin folds. If too much irritation occurs after using this medication, stop using this medication and tell your doctor.

Treatment is usually continued until the affected area is entirely clear.

Tell your doctor if your condition persists or worsens.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist.