Drituss HD

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Hydrocodone is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Guaifenesin, hydrocodone, and pseudoephedrine is a combination medicine used to treat cough, stuffy nose, and sinus congestion caused by allergies or the common cold.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Guaifenesin, hydrocodone, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of hydrocodone can be fatal.

Overdose symptoms may include confusion, extreme weakness, pinpoint pupils, cold and clammy skin, weak pulse, slow breathing, fainting, or breathing that stops.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• severe dizziness or drowsiness;

• weak or shallow breathing;

• severe restlessness or nervousness;

• severe constipation;

• pounding heartbeats or fluttering in your chest;

• painful or difficult urination; or

• little or no urinating.

Common side effects may include:

• mild drowsiness;

• dryness of your eyes, nose, and mouth;

• blurred vision; or

• nausea, vomiting, diarrhea, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Guaifenesin/hydrocodone/pseudoephedrine 200 mg-6 mg-45 mg/5 mL:
6 to 11 years: 2.5 mL orally every 4 to 6 hours not to exceed 12.5 mL daily.
12 years or older: 5 mL orally every 4 to 6 hours not to exceed 25 mL daily.

Guaifenesin/hydrocodone/pseudoephedrine 50 mg-3.75 mg-22.5 mg/5 mL oral liquid:
2 to 5 years: 2.5 mL orally every 4 to 6 hours not to exceed 10 mL daily.
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Guaifenesin/hydrocodone/pseudoephedrine is listed as a Schedule II drug under the Federal Controlled Substances Act of 1970.

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