Dry-Clox

Name: Dry-Clox

Dry Clox Drug Class

Dry Clox is part of the drug class:

  • Beta lactamase resistant penicillins

Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Storage

Do not store above 25°C (77°F). Do not freeze.

Action

In the non-lactating mammary gland, Dry-Clox (cloxacillin benzathine) provides bactericidal levels of the active antibiotic, cloxacillin, for a prolonged period of time. This prolonged activity is due to the low solubility of the cloxacillin benzathine and to the slow-release oil-gel base. This prolonged contact between the antibiotic and the pathogenic organism enhances the probability of a bacteriological cure.

Cloxacillin is not destroyed by the enzyme, penicillinase, and therefore, is active against penicillin-resistant strains of Staphylococcus aureus. It is also active against non-penicillinase-producing Staphylococcus aureus as well as Streptococcus agalactiae.

The class disc, Methicillin 5 mcg, should be used to estimate the in vitro susceptibility of bacteria to cloxacillin.

Indications

For the treatment of mastitis in dairy cows during the dry period.

Dry-Clox has been shown by extensive clinical studies to be efficacious in the treatment of mastitis in dry cows, when caused by Streptococcus agalactiae and Staphylococcus aureus including penicillin-resistant strains.

Treatment of the dry cow with Dry-Clox is indicated in any cow known to harbor any of these organisms in the udder at drying off, or which has had repeated attacks of mastitis during the previous lactation, or is affected with mastitis at drying off, if caused by susceptible organisms.

Residue Warnings

1. For use in dry cows only.

2. Not to be used within 30 days of calving.

3. Any animal infused with this product must not be slaughtered

for food until 30 days after the latest infusion.

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