Desonide

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Desonide falls into category C:

In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans, though. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

OR

There are no well-controlled studies that have been done in pregnant women. Desonide should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

OR

No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Desonide should be given to a pregnant woman only if clearly needed.

Storage

Topical

Foam: 20–25°C; contents under pressure, do not puncture or incinerate.d Flammable; avoid fire, flame, smoking, and/or exposure to >120°C.d

Gel: 25°C (may be exposed to 15–30°C).f

Cream, lotion, and ointment: 2–30°C; do not freeze.c e g h

In controlled clinical trials, the total incidence of adverse reactions associated with the use of Desonide ointment, 0.05% was approximately 6%. These adverse reactions were erythema, induration, pruritus, irritation, oiliness, and peripheral edema.

The following additional local adverse reactions have been reported infrequently with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids. These reactions are listed in approximate decreasing order of occurrence: dryness, folliculitis, acneiform eruptions, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, miliaria, burning and hypopigmentation.

(DES oh nide)

There are no dosage adjustments provided in the manufacturer's labeling.

There are no dosage adjustments provided in the manufacturer's labeling.

Cream, lotion, ointment: Store between 2°C and 30°C (36°F and 86°F). Store Tridesilon cream at 20°C to 25°C (68°F to 77°F).

Foam: Store between 20°C and 25°C (68°F and 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F). Foam is flammable; keep away from excessive heat (eg, temperatures >49°C [120°F], fire or flames. Do not puncture or incinerate container.

Gel: Store at 25°C (77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).

Adverse events have been observed in animal reproduction studies.

Applies to desonide topical: topical application cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment

Along with its needed effects, desonide topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking desonide topical:

• Blistering, burning, crusting, dryness, or flaking of the skin
• burning, itching, redness, skin rash, swelling, or soreness at the application site
• flushing or redness of the skin
• irritation
• itching, scaling, severe redness, soreness, or swelling of the skin
• peeling of the skin
• raised, dark red, wart-like spots on the skin, especially when used on the face
• stinging and burning
• unusually warm skin

• Redness and scaling around the mouth
• thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g., between the fingers)

Some side effects of desonide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Body aches or pain
• chills
• cough
• difficulty with breathing
• ear congestion
• fever
• headache
• loss of voice
• nasal congestion
• runny nose
• sneezing
• sore throat
• unusual tiredness or weakness

• Cold flu-like symptoms
• congestion
• cough
• hoarseness
• irritability
• noisy breathing
• shortness of breath
• tender, swollen glands in the neck
• tightness in the chest
• trouble with swallowing
• voice changes
• wheezing

• Acne or pimples
• burning and itching of the skin with pinhead-sized red blisters
• burning, itching, and pain in hairy areas, or pus at the root of the hair
• lightening of normal skin color
• lightening of treated areas of dark skin
• reddish purple lines on the arms, face, legs, trunk, or groin

Cream/ointment: Apply a thin film to the affected areas two to four times per day depending on the severity of the condition
Duration of therapy: 2 weeks

Comments:
-Treatment should be discontinued when control is achieved.
-Reassessment of diagnosis may be needed, if no improvement is observed in two weeks.
-This topical drug should not be used with occlusive dressings.

Use: Relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses

3 months or older:
Foam, gel: Apply a thin film to the affected areas two times a day and rub in gently.
Duration of therapy: 4 weeks

Comments:
-Treatment should be discontinued when control is achieved.
-Reassessment of diagnosis may be needed, if no improvement is observed in four weeks.
-This topical drug should not be used with occlusive dressings.

Use: Treatment of mild to moderate atopic dermatitis