Cetiri D

Cetiri-D is part of the drug classes:

• Piperazine derivatives

• Sympathomimetics

Applies to cetirizine / pseudoephedrine: oral tablet extended release

Dermatologic

Dermatologic side effects have included maculopapular and urticarial eruptions.[Ref]

Gastrointestinal

Gastrointestinal side effects of cetirizine have included dry mouth (5.7%) and nausea or vomiting (2.2%). Pharyngitis, dyspepsia, and increased appetite have occasionally been reported.

Gastrointestinal adverse effects of pseudoephedrine have included anorexia and gastric irritation (5%). Dry mouth, nose, or throat have occurred in up to 15% of patients.[Ref]

Hepatic

Hepatic side effects have included rare liver function test abnormalities which resolved spontaneously following discontinuation of cetirizine therapy.[Ref]

Nervous system

Cetirizine appears to be more sedating than terfenadine, astemizole, and loratadine.[Ref]

Nervous system side effects of cetirizine administration have included headache (16%), fatigue (5.6%), and somnolence (5% to 20%). Somnolence tends to be dose-related and generally occurs more frequently with doses higher than 10 mg per day. Other nervous system side effects include dizziness (1.8%), insomnia (1.5%), and nervousness (1.1%). Post marketing reports have included aggression reaction and convulsions.

Nervous system side effects of pseudoephedrine have included insomnia in up to 30% of patients. Tremor, anxiety, nervousness, and headache have also been reported.[Ref]

Respiratory

Respiratory side effects have included wheezing, coughing, bronchitis, sinusitis, and asthma.[Ref]

Hypersensitivity

Hypersensitivity reactions have included fixed drug eruptions with pseudoephedrine use.[Ref]

Cardiovascular

Cardiovascular side effects have included tachycardia. Some patients have developed hypertension and/or arrhythmias.[Ref]

General

General side effects have included epistaxis (1.1%) and accidental injury (1.1%).[Ref]

Some side effects of Cetiri D may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.