Cantil

You should not take this medication if you are allergic to mepenzolate, or if you have:

• problems with urination;
• a blockage in your intestines, paralytic ileus, severe ulcerative colitis, toxic megacolon;
• glaucoma; or
• myasthenia gravis.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take mepenzolate:

• diarrhea (especially if you have a colostomy or ileostomy);
• numbness or tingling in your hands or feet;
• liver or kidney disease;
• ulcerative colitis;
• overactive thyroid;
• congestive heart failure, a heart rhythm disorder, or coronary artery disease;
• high blood pressure (hypertension);
• hiatal hernia or acid reflux disease;
• an enlarged prostate; or
• asthma or any allergies.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether mepenzolate passes into breast milk or if it could harm a nursing baby. Do not take mepenzolate without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from mepenzolate.

Mepenzolate reduces stomach acid and helps control muscle spasms in the intestines.

Mepenzolate is used to treat peptic ulcers of the stomach. Mepenzolate does not help heal an ulcer.

Mepenzolate may also be used for purposes other than those listed in this medication guide.

Use Cantil as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with meals and at bedtime.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Very bad dizziness or passing out.
• Feeling very tired or weak.
• Big change in balance.
• A fast heartbeat.
• A heartbeat that does not feel normal.
• Feeling confused.
• Mood changes.
• Hallucinations (seeing or hearing things that are not there).
• Memory problems or loss.
• Not able to sleep.
• Trouble speaking.
• Change in eyesight.
• Loose stools (diarrhea).
• Change in sex ability.
• Not able to pass urine.
• Not sweating during activities or in warm temperatures.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Cantil or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cantil. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

1. Glaucoma
2. Obstructive uropathy (for example, bladder neck obstruction due to prostatic hypertrophy)
3. Obstructive disease of the gastrointestinal tract (for example, pyloroduodenal stenosis, achalasia)
4. Paralytic ileus
5. Intestinal atony of the elderly or debilitated patient (See PRECAUTIONS, Geriatric Use)
6. Unstable cardiovascular status in acute gastrointestinal hemorrhage
7. Toxic megacolon complicating ulcerative colitis
8. Myasthenia gravis
9. Allergic or idiosyncratic reactions to Cantil or related compounds

In the presence of high environmental temperature, heat prostration (fever and heat stroke due to decreased sweating) can occur with use of Cantil.

Diarrhea may be an early symptom of incomplete intestinal obstruction especially in patients with ileostomy or colostomy. In this instance, treatment with this drug would be inappropriate and possibly harmful.

Cantil may produce drowsiness or blurred vision. The patient should be cautioned regarding activities requiring mental alertness such as operating a motor vehicle or other machinery or performing hazardous work while taking this drug.

With overdosage, a curare-like action may occur i.e., neuromuscular blockage leading to muscular weakness and possible paralysis.

It should be noted that the use of anticholinergic drugs in the treatment of gastric ulcer may produce a delay in gastric emptying time and may complicate such therapy (antral stasis).

Psychosis has been reported in sensitive individuals given anticholinergic drugs. CNS signs and symptoms include confusion, disorientation, short-term memory loss, hallucinations, dysarthria, ataxia, coma, euphoria, decreased anxiety, fatigue, insomnia, agitation and mannerisms and inappropriate affect. These CNS signs and symptoms usually resolve within 12 to 24 hours after discontinuation of the medication.

Tolerance, abuse, or dependence has not been reported with Cantil.