Bacitracin Zinc eent

Absorption

Extent

Not substantially absorbed from intact or denuded skin, wounds, or mucous membranes.a

Distribution

Extent

Not known whether topical bacitracin is distributed into breast milk.e g

Storage

Ophthalmic

Bacitracin: 15–30°C.a

Bacitracin zinc and polymyxin B sulfate: 20–25°C.d

Neomycin and polymyxin B sulfates and bacitracin zinc: 20–25°C.e

Neomycin and polymyxin B sulfates and bacitracin zinc with hydrocortisone: 15–30°C.f

Neomycin and polymyxin B sulfates and bacitracin zinc with hydrocortisone acetate: 15–25°C.104

• Importance of not touching tip of container to the eye, eyelid, fingers, or any other surface to avoid contamination.101 104 e f Advise patient to keep container tightly closed when not in use.e f

• Importance of discontinuing therapy and contacting clinician if the infection worsens or does not improve, or if any signs of sensitivity occur (e.g., rash, itching, swelling, redness, burning).101 104 a e f

• Advise patient not to share the drug with any other person.104 e

• Importance of informing clinician of existing or contemplated concomitant therapy, including prescription and OTC drugs as well as any concomitant illnesses.104 d e

• Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.104 e

• Importance of informing patients of other important precautionary information. (See Cautions.)

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name