Bacitracin, neomycin, and polymyxin B topical

Name: Bacitracin, neomycin, and polymyxin B topical

How should I use this medicine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Before you apply this medication, wash the skin area with soap and water and then dry it thoroughly.

Do not apply the ointment over large skin areas. Do not use on a deep cut, an animal bite, or a serious burn. Contact your doctor for instructions on how to treat these more severe skin injuries.

This medication can be applied up to 3 times each day, or as directed on the medicine label. Cover the wound with a bandage if desired. Clean the wound and use a new bandage each time you apply the medicine.

Use the ointment for as many days as recommended on the label or by your doctor, even if your symptoms start getting better. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if they get worse while using bacitracin, neomycin, and polymyxin B topical.

Store at room temperature away from moisture and heat. Throw away any ointment not used before the expiration date on the medicine label.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

How is this medicine (Bacitracin, Neomycin, and Polymyxin B) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • To gain the most benefit, do not miss doses.
  • Use as you have been told, even if your signs get better.
  • Do not take bacitracin, neomycin, and polymyxin B by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
  • Clean affected part before use. Make sure to dry well.
  • Put a thin layer on the affected skin and rub in gently.
  • The treated part may be covered with a dressing.

What do I do if I miss a dose?

  • Put on a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not put on 2 doses at the same time or extra doses.

What are some other side effects of Bacitracin, Neomycin, and Polymyxin B?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Skin irritation.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Use Labeled Indications

Topical infection prevention: Prevention of infection in minor cuts

Dosing Renal Impairment

There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.

Adverse Reactions

Frequency not defined.

Dermatologic: Reddening, allergic contact dermatitis

Local: Itching, failure to heal, swelling, irritation

Miscellaneous: Anaphylaxis

Warnings/Precautions

Dosage form specific issues:

• Topical ointment: When used for self-medication (OTC use), patients should notify healthcare provider if needed for >1 week. Should not be used for self-medication on deep or puncture wounds, animal bites, or serious burns. Not for application to large areas of the body.

Pregnancy Risk Factor C Pregnancy Considerations

Animal reproduction studies have not been conducted with this combination.

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