Bacitracin, Neomycin, and Polymyxin B (Ophthalmic)

Name: Bacitracin, Neomycin, and Polymyxin B (Ophthalmic)

Uses of Bacitracin, Neomycin, and Polymyxin B

  • It is used to treat eye infections.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take bacitracin, neomycin, and polymyxin B or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to bacitracin, neomycin, and polymyxin B. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Ointment, Ophthalmic:

Neo-Polycin: Bacitracin 400 units, neomycin 3.5 mg, and polymyxin B 10,000 units per g (3.5 g)

Generic: Bacitracin 400 units, neomycin 3.5 mg, and polymyxin B 10,000 units per g (3.5 g)

Dosing Pediatric

Conjunctivitis (off-label): Limited data available: Children and Adolescents: Ophthalmic: Ointment: Apply 0.5 inch ribbon every 3 to 4 hours for acute infections, or 2 to 3 times per day for mild to moderate infections, for 7 to 10 days (Pichichero 2011).

Dosing Renal Impairment

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing Hepatic Impairment

There are no dosage adjustments provided in the manufacturer’s labeling.

Drug Interactions

There are no known significant interactions.

Bacitracin, neomycin, and polymyxin B ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • severe itching, watering, redness, or swelling of your eyes;

  • eye pain;

  • crusting or drainage from your eyes; or

  • any new signs of infection.

Less serious side effects may include temporary blurred vision and mild eye irritation after using the ointment.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For Healthcare Professionals

Applies to bacitracin / neomycin / polymyxin b ophthalmic: ophthalmic ointment

Hypersensitivity

Hypersensitivity reactions including itching, swelling and conjunctival erythema have been reported. Anaphylaxis and other more serious hypersensitivity reactions have been reported rarely.[Ref]

Local

Local side effects have included irritation upon administration.[Ref]

Some side effects of bacitracin / neomycin / polymyxin b ophthalmic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Usual Adult Dose for Blepharoconjunctivitis

Apply to the affected eye(s) every 3 to 4 hours for 7 to 10 days

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