Antihemophilic Factor (Recombinant) (Kovaltry, Novoeight, and Nuwiq)

• It is used to treat hemophilia.
• It is used to treat or prevent bleeding.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• A burning, numbness, or tingling feeling that is not normal.
• Change in color of mouth to blue.
• Chest pain or pressure or a fast heartbeat.
• Dizziness or passing out.
• Feeling cold.
• Fever or chills.
• Flushing.
• Pale skin.
• Restlessness.
• Shortness of breath.
• Trouble swallowing.
• Upset stomach or throwing up.

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

All products:

• If this medicine is given at home, store unopened containers at room temperature or in the refrigerator. Do not freeze.
• Store in original container.
• If stored at room temperature, make a note of the date it was placed at room temperature.
• Protect from light.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Check with your pharmacist about how to throw out unused drugs.

Kovaltry and Novoeight:

• If stored at room temperature, throw away any unused vials after 12 months or after the expiration date, whichever comes first.
• Do not put antihemophilic factor back in the refrigerator after it has been stored at room temperature.

Nuwiq:

• If stored at room temperature, throw away any unused vials after 3 months or after the expiration date, whichever comes first.
• Do not put antihemophilic factor back in the refrigerator after it has been stored at room temperature.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about antihemophilic factor, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about antihemophilic factor (recombinant) (kovaltry, novoeight, and nuwiq). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using antihemophilic factor.

Review Date: October 4, 2017