Antivert

Name: Antivert

What is meclizine?

Meclizine is an antihistamine that reduces the effects of natural chemical histamine in the body.

Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. Meclizine is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear.

Meclizine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about meclizine?

You should not take this medication if you are allergic to meclizine.

Before you take meclizine, tell your doctor if you have liver or kidney disease, asthma, glaucoma, an enlarged prostate, or urination problems.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of meclizine.

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by meclizine.

Uses For Antivert

Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems.

Meclizine is an antihistamine. It works to block the signals to the brain that cause nausea, vomiting, and dizziness.

This medicine is available only with your doctor's prescription.

Uses of Antivert

  • It is used to help motion sickness.
  • It is used to treat dizziness (vertigo).
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Antivert?

  • If you have an allergy to meclizine or any other part of Antivert (meclizine capsules and tablets).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

How do I store and/or throw out Antivert?

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Antivert Description

Chemically, Antivert® (meclizine HCl) is 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine dihydrochloride monohydrate.

Inert ingredients for the tablets are: dibasic calcium phosphate; magnesium stearate; polyethylene glycol; starch; sucrose. The 12.5 mg tablets also contain: Blue 1. The 25 mg tablets also contain: Yellow 6 Lake; Yellow 10 Lake. The 50 mg tablets also contain: Blue 1 Lake; Yellow 10 Lake.

Contraindications

Meclizine HCl is contraindicated in individuals who have shown a previous hypersensitivity to it.

PRINCIPAL DISPLAY PANEL - 50 mg Tablet Label

NDC 0049-2140-66

100 Tablets

Antivert®
(meclizine HCl)

50 mg

Pfizer
Distributed by
Roerig
Division of Pfizer Inc, NY, NY 10017

Antivert 
meclizine hydrochloride tablet
Product Information
Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0049-2100
Route of Administration ORAL DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
MECLIZINE HYDROCHLORIDE (MECLIZINE) MECLIZINE HYDROCHLORIDE 12.5 mg
Inactive Ingredients
Ingredient Name Strength
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUS  
MAGNESIUM STEARATE  
POLYETHYLENE GLYCOLS  
SUCROSE  
FD&C BLUE NO. 1  
Product Characteristics
Color BLUE, WHITE Score no score
Shape OVAL Size 10mm
Flavor Imprint Code Antivert;210
Contains     
Packaging
# Item Code Package Description
1 NDC:0049-2100-66 100 TABLET in 1 BOTTLE
2 NDC:0049-2100-82 1000 TABLET in 1 BOTTLE
Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
NDA NDA010721 04/11/1997
Antivert 
meclizine hydrochloride tablet
Product Information
Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0049-2110
Route of Administration ORAL DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
MECLIZINE HYDROCHLORIDE (MECLIZINE) MECLIZINE HYDROCHLORIDE 25 mg
Inactive Ingredients
Ingredient Name Strength
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUS  
MAGNESIUM STEARATE  
POLYETHYLENE GLYCOLS  
SUCROSE  
FD&C YELLOW NO. 6  
D&C YELLOW NO. 10  
ALUMINUM OXIDE  
Product Characteristics
Color YELLOW, WHITE Score no score
Shape OVAL Size 13mm
Flavor Imprint Code Antivert;211
Contains     
Packaging
# Item Code Package Description
1 NDC:0049-2110-66 100 TABLET in 1 BOTTLE
2 NDC:0049-2110-82 1000 TABLET in 1 BOTTLE
Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
NDA NDA010721 04/11/1997
Antivert 
meclizine hydrochloride tablet
Product Information
Product Type HUMAN PRESCRIPTION DRUG LABEL Item Code (Source) NDC:0049-2140
Route of Administration ORAL DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
MECLIZINE HYDROCHLORIDE (MECLIZINE) MECLIZINE HYDROCHLORIDE 50 mg
Inactive Ingredients
Ingredient Name Strength
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUS  
MAGNESIUM STEARATE  
POLYETHYLENE GLYCOLS  
SUCROSE  
FD&C BLUE NO. 1  
D&C YELLOW NO. 10  
ALUMINUM OXIDE  
Product Characteristics
Color YELLOW, BLUE Score 2 pieces
Shape OVAL Size 16mm
Flavor Imprint Code Antivert;214
Contains     
Packaging
# Item Code Package Description
1 NDC:0049-2140-66 100 TABLET in 1 BOTTLE
Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
NDA NDA010721 04/11/1997
Labeler - Roerig (829076996)
Establishment
Name Address ID/FEI Operations
UCB Pharma S.A. 372274485 MANUFACTURE(0049-2140, 0049-2110, 0049-2100)
Establishment
Name Address ID/FEI Operations
Pfizer Pharmaceuticals LLC 829084545 API MANUFACTURE(0049-2140)
Revised: 11/2012   Roerig

Side effects

Anaphylactoid reaction, drowsiness, dry mouth, headache, fatigue, vomiting and, on rare occasions, blurred vision have been reported.

Read the entire FDA prescribing information for Antivert (Meclizine)

Read More »

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

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