Antacid

Name: Antacid

Before Using This Medicine

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Antacids should not be given to young children (under 6 years of age) unless ordered by their doctor. Since children cannot usually describe their symptoms very well, a doctor should first check the child. The child may have a condition that needs other treatment. If so, antacids will not help and may even cause unwanted effects or make the condition worse. In addition, aluminum- or magnesium-containing medicines should not be given to premature or very young children because they may cause serious side effects, especially when given to children who have kidney disease or who are dehydrated.

Geriatric

Aluminum-containing antacids should not be used by elderly persons with bone problems or with Alzheimer's disease. The aluminum may cause their condition to get worse.

Pregnancy

Studies on effects in pregnancy have not been done in either humans or animals. However, there have been reports of antacids causing side effects in babies whose mothers took antacids for a long time, especially in high doses during pregnancy. Also, sodium-containing medicines should be avoided if you tend to retain (keep) body water.

Breast Feeding

Some aluminum-, calcium-, or magnesium-containing antacids may pass into breast milk. However, these medicines have not been reported to cause problems in nursing babies.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Amantadine
  • Amifampridine
  • Amisulpride
  • Atropine
  • Belladonna
  • Belladonna Alkaloids
  • Benztropine
  • Bepridil
  • Biperiden
  • Cisapride
  • Clidinium
  • Darifenacin
  • Dicyclomine
  • Dronedarone
  • Eplerenone
  • Fesoterodine
  • Glycopyrrolate
  • Hyoscyamine
  • Mesoridazine
  • Methscopolamine
  • Oxybutynin
  • Pimozide
  • Piperaquine
  • Procyclidine
  • Saquinavir
  • Scopolamine
  • Solifenacin
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Tolterodine
  • Trihexyphenidyl
  • Trospium
  • Ziprasidone

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aceclofenac
  • Acemetacin
  • Alacepril
  • Amiloride
  • Amiodarone
  • Amphetamine
  • Amprenavir
  • Amtolmetin Guacil
  • Anagrelide
  • Aripiprazole
  • Aripiprazole Lauroxil
  • Arsenic Trioxide
  • Atazanavir
  • Benazepril
  • Benzphetamine
  • Bromfenac
  • Bufexamac
  • Bupropion
  • Buserelin
  • Canrenoate
  • Captopril
  • Celecoxib
  • Cilazapril
  • Clarithromycin
  • Clonixin
  • Clozapine
  • Crizotinib
  • Dabrafenib
  • Dasatinib
  • Deferasirox
  • Degarelix
  • Delamanid
  • Delapril
  • Delavirdine
  • Deslorelin
  • Deutetrabenazine
  • Dexibuprofen
  • Dexketoprofen
  • Dextroamphetamine
  • Diclofenac
  • Digoxin
  • Dipyrone
  • Domperidone
  • Donepezil
  • Droxicam
  • Efavirenz
  • Elvitegravir
  • Enalaprilat
  • Enalapril Maleate
  • Erlotinib
  • Escitalopram
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Fluconazole
  • Flufenamic Acid
  • Fluoxetine
  • Flurbiprofen
  • Fosamprenavir
  • Foscarnet
  • Fosinopril
  • Gefitinib
  • Gonadorelin
  • Goserelin
  • Histrelin
  • Hydroxychloroquine
  • Hydroxyzine
  • Ibuprofen
  • Imidapril
  • Indomethacin
  • Ivabradine
  • Ketoconazole
  • Ketoprofen
  • Ledipasvir
  • Leuprolide
  • Levofloxacin
  • Licorice
  • Lisdexamfetamine
  • Lisinopril
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Memantine
  • Methadone
  • Methamphetamine
  • Metronidazole
  • Moexipril
  • Morniflumate
  • Moxifloxacin
  • Mycophenolate Mofetil
  • Mycophenolic Acid
  • Nabumetone
  • Nafarelin
  • Naproxen
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Ondansetron
  • Oxaprozin
  • Oxyphenbutazone
  • Panobinostat
  • Parecoxib
  • Pasireotide
  • Pazopanib
  • Pentopril
  • Perindopril
  • Phenylbutazone
  • Phenytoin
  • Piketoprofen
  • Pimavanserin
  • Piroxicam
  • Pitolisant
  • Posaconazole
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Quetiapine
  • Quinapril
  • Quinine
  • Raltegravir
  • Ramipril
  • Ribociclib
  • Rilpivirine
  • Rofecoxib
  • Sevoflurane
  • Sotalol
  • Spirapril
  • Spironolactone
  • Sulindac
  • Sulpiride
  • Tacrolimus
  • Temocapril
  • Tenoxicam
  • Tiaprofenic Acid
  • Tizanidine
  • Tolazoline
  • Tolfenamic Acid
  • Tolmetin
  • Trandolapril
  • Triamterene
  • Triptorelin
  • Valdecoxib
  • Vandetanib
  • Vemurafenib
  • Vinflunine
  • Vismodegib
  • Zofenopril
  • Zuclopenthixol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alzheimer's disease (for aluminum-containing antacids only) or
  • Appendicitis (or signs of) or
  • Bone fractures or
  • Colitis or
  • Constipation (severe and continuing) or
  • Hemorrhoids or
  • Intestinal blockage or
  • Intestinal or rectal bleeding—Antacids may make these conditions worse
  • Colostomy or
  • Ileostomy or
  • Inflamed bowel—Use of antacids may cause the body to retain (keep) water and electrolytes such as sodium and/or potassium
  • Edema (swelling of feet or lower legs) or
  • Heart disease or
  • Liver disease or
  • Toxemia of pregnancy—Use of sodium-containing antacids may cause the body to retain (keep) water
  • Kidney disease—Antacids may cause higher blood levels of aluminum, calcium, or magnesium, which may increase the risk of serious side effects
  • Sarcoidosis—Use of calcium-containing antacids may cause kidney problems or too much calcium in the blood
  • Underactive parathyroid glands—Use with calcium-containing antacids may cause too much calcium in the blood

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Along with its needed effects, a medicine may cause some unwanted effects. Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more likely to occur if: too much medicine is taken; it is taken in large doses; it is taken for a long time; or it is taken by patients with kidney disease.

Check with your doctor as soon as possible if any of the following side effects occur:

For aluminum-containing antacids (including magaldrate)
  • Bone pain
  • constipation (severe and continuing)
  • feeling of discomfort (continuing)
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle weakness
  • swelling of wrists or ankles
  • weight loss (unusual)
For calcium-containing antacids
  • Constipation (severe and continuing)
  • difficult or painful urination
  • frequent urge to urinate
  • headache (continuing)
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • nausea or vomiting
  • nervousness or restlessness
  • slow breathing
  • unpleasant taste
  • unusual tiredness or weakness
For magnesium-containing antacids (including magaldrate)
  • Difficult or painful urination (with magnesium trisilicate)
  • dizziness or lightheadedness
  • feeling of discomfort (continuing)
  • irregular heartbeat
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle weakness
  • unusual tiredness or weakness
  • weight loss (unusual)
For sodium bicarbonate-containing antacids
  • Frequent urge to urinate
  • headache (continuing)
  • loss of appetite (continuing)
  • muscle pain or twitching
  • nausea or vomiting
  • nervousness or restlessness
  • slow breathing
  • swelling of feet or lower legs
  • unpleasant taste
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Chalky taste
Less common
  • Constipation (mild)
  • diarrhea or laxative effect
  • increased thirst
  • speckling or whitish discoloration of stools
  • stomach cramps

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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