Amphotericin Injectable Solution

AMPHOTERICIN (am foe TER i sin) B CHOLESTERYL SULFATE COMPLEX is an antifungal medicine. It is used to treat certain kinds of fungal or yeast infections.

This drug also comes in other forms, including Injectable suspension

This drug can cause serious side effects. See which side effects you should report to your doctor right away.

Know how to use your medication, and learn what might happen if you miss a dose.

Talk to your healthcare provider if you have any of these conditions.

Know what to watch for and get tips for reducing your risks while taking this drug.

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
• anxiety, confusion
• breathing trouble
• burning, numbness, tingling
• change in amount or color of urine
• change in hearing, vision
• chest tightness
• fever, chills, infection
• irregular heart beat, blood pressure
• seizure
• unusual bleeding, bruising
• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• body aches, pain
• cough
• diarrhea
• headache
• flushing, redness of skin
• nausea, vomiting
• pain where injected
• stomach pain
• trouble sleeping

Do not take this medicine with any of the following medications:

• cidofovir

This medicine may also interact with the following medications:

• certain antibiotics given by injection
• corticotropin
• cyclosporine
• digoxin
• entecavir
• flucytosine
• medicines for fungal infections
• medicines to treat cancer
• muscle relaxers
• pentamidine
• steroid medicines like prednisone or cortisone

This medicine is for infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

They need to know if you have any of these conditions:

• immune system problems
• other chronic illness
• an unusual or allergic reaction to amphotericin B, other medicines, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or health care professional if your symptoms do not improve or if you get new symptoms.

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.