Zacare

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

This medication comes as a kit containing benzoyl peroxide lotion and sodium hyaluronate gel.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Benzoyl peroxide can cause rare but serious allergic reactions or severe skin irritation. Before you start using this medicine, you may choose to apply a "test dose" to see if you have a reaction. Apply a very small amount of the medicine to 1 or 2 small acne areas every day for 3 days in a row. If there is no reaction, begin using the full prescribed amount on the 4th day.

Shake the benzoyl peroxide lotion well just before each use.

Wet the skin before applying the benzoyl peroxide cleansing lotion. Work the lotion into a lather and rinse thoroughly. Gently pat the skin dry.

During your first week of treatment, wash the affected skin with the benzoyl peroxide lotion once daily. After the first week, wash the skin twice daily.

The sodium hyaluronate gel may be applied 2 or 3 times daily. Follow your doctor's instructions. Apply a liberal amount of the gel and rub it in thoroughly.

Do not cover the treated skin area unless your doctor tells you to.

It may take up to 3 weeks before your symptoms improve. The best results may be seen after 8 to 12 weeks of use. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat. Keep the lotion bottle and ointment tube tightly closed when not in use.

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have severe stinging or burning of your skin.

Common side effects may include:

• redness or peeling of treated skin;

• mild burning or stinging; or

• dry skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

It is not likely that other drugs you take orally or inject will have an effect on topically applied benzoyl peroxide and sodium hyaluronate. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.